Background During pregnancy, fetal cells suitable for genetic testing can be obtained from
amniotic fluid by amniocentesis (AC), placental tissue by chorionic villus sampling (CVS), or …

Introduction: As a consequence of the introduction of effective screening methods, the
number of invasive prenatal diagnostic procedures is steadily declining. The aim of this …

Cytogenetics is the study of chromosome morphology, structure, pathology, function, and
behavior. The field has evolved to embrace molecular cytogenetic changes, now termed …

Although clubfoot is one of the most common congenital abnormalities affecting the lower
limb, it remains a challenge not only to understand its genetic origins but also to provide …

ISUOG Practice Guidelines: invasive procedures for prenatal diagnosis ISUOG Practice
Guidelines: invasive procedures for prenatal diagnosis Ultrasound Obstet Gynecol. 2016 …

Idiopathic congenital clubfoot is the most common serious musculoskeletal birth defect in the
United States and the world. The natural history of the deformity is to persist into adult life …

Clubfoot is a common structural malformation, occurring in approximately 1/1,000 live births.
Previous studies of sociodemographic and pregnancy‐related risk factors have been …

Background: Clubfoot is a common congenital anomaly with multiple potential risk factors.
Identification of modifiable risk factors may minimize future incidence of clubfoot. The aim of …

The present disclosure provides methods for determining the ploidy status of a chromosome
in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising …

The invention provides methods, systems, and computer readable medium for detecting
ploidy of chromosome segments or entire chromosomes, for detecting single nucleotide …