[HTML][HTML] Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization

JM Bolivar, JM Woodley… - Chemical Society …, 2022 - pubs.rsc.org
Enzyme immobilization has been developing since the 1960s and although many industrial
biocatalytic processes use the technology to improve enzyme performance, still today we …

A brief introduction to chemical reaction optimization

CJ Taylor, A Pomberger, KC Felton, R Grainger… - Chemical …, 2023 - ACS Publications
From the start of a synthetic chemist's training, experiments are conducted based on recipes
from textbooks and manuscripts that achieve clean reaction outcomes, allowing the scientist …

Photons or electrons? A critical comparison of electrochemistry and photoredox catalysis for organic synthesis

NES Tay, D Lehnherr, T Rovis - Chemical reviews, 2021 - ACS Publications
Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …

Photocatalysis in the life science industry

L Candish, KD Collins, GC Cook, JJ Douglas… - Chemical …, 2021 - ACS Publications
In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science
industry require access to mild and robust synthetic methodologies to systematically modify …

Exploring catalytic reaction networks with machine learning

JT Margraf, H Jung, C Scheurer, K Reuter - Nature Catalysis, 2023 - nature.com
Chemical reaction networks form the heart of microkinetic models, which are one of the key
tools available for gaining detailed mechanistic insight into heterogeneous catalytic …

Organic reaction mechanism classification using machine learning

J Burés, I Larrosa - Nature, 2023 - nature.com
A mechanistic understanding of catalytic organic reactions is crucial for the design of new
catalysts, modes of reactivity and the development of greener and more sustainable …

Mechanism of Ni-catalyzed reductive 1, 2-dicarbofunctionalization of alkenes

Q Lin, T Diao - Journal of the American Chemical Society, 2019 - ACS Publications
Ni-catalyzed cross-electrophile coupling reactions have emerged as appealing methods to
construct organic molecules without the use of stoichiometric organometallic reagents. The …

[HTML][HTML] Automation isn't automatic

M Christensen, LPE Yunker, P Shiri, T Zepel… - Chemical …, 2021 - pubs.rsc.org
Automation has become an increasingly popular tool for synthetic chemists over the past
decade. Recent advances in robotics and computer science have led to the emergence of …

The high chemofidelity of metal-catalyzed hydrogen atom transfer

SA Green, SWM Crossley, JLM Matos… - Accounts of chemical …, 2018 - ACS Publications
Conspectus The implementation of any chemical reaction in a structurally complex setting
(King, SMJ Org. Chem. 2014, 79, 8937) confronts structurally defined barriers: steric …

Variable time normalization analysis: general graphical elucidation of reaction orders from concentration profiles

J Burés - Angewandte Chemie, 2016 - Wiley Online Library
The recent technological evolution of reaction monitoring techniques has not been
paralleled by the development of modern kinetic analyses. The analyses currently used …