IMI–Report on experimental models of emmetropization and myopia

D Troilo, EL Smith, DL Nickla, R Ashby… - … & visual science, 2019 - iovs.arvojournals.org
The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

Circadian rhythms, refractive development, and myopia

R Chakraborty, LA Ostrin, DL Nickla… - Ophthalmic and …, 2018 - Wiley Online Library
Purpose Despite extensive research, mechanisms regulating postnatal eye growth and
those responsible for ametropias are poorly understood. With the marked recent increases …

[HTML][HTML] Understanding glaucomatous damage: anatomical and functional data from ocular hypertensive rodent retinas

M Vidal-Sanz, M Salinas-Navarro… - Progress in retinal and …, 2012 - Elsevier
Glaucoma, the second most common cause of blindness, is characterized by a progressive
loss of retinal ganglion cells and their axons, with a concomitant loss of the visual field …

Circadian organization of the mammalian retina: from gene regulation to physiology and diseases

DG McMahon, PM Iuvone, G Tosini - Progress in retinal and eye research, 2014 - Elsevier
The retinal circadian system represents a unique structure. It contains a complete circadian
system and thus the retina represents an ideal model to study fundamental questions of how …

Understanding mechanisms of pressure-induced optic nerve damage

JC Morrison, EC Johnson, W Cepurna, L Jia - Progress in retinal and eye …, 2005 - Elsevier
Patients with glaucoma can suffer progressive vision loss, even in the face of what appears
to be excellent intraocular pressure (IOP) control. Some of this may be secondary to non …

[HTML][HTML] Chronology of optic nerve head and retinal responses to elevated intraocular pressure

EC Johnson, LMH Deppmeier… - … & visual science, 2000 - arvojournals.org
purpose. To determine the chronology of optic nerve head and retinal responses to elevated
intraocular pressure (IOP). methods. After 1 to 39 days of unilaterally elevated IOP …

Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure

F Ahmed, KM Brown, DA Stephan… - … & visual science, 2004 - iovs.arvojournals.org
purpose. The goal of this study was to identify altered patterns of retinal mRNA expression
after experimental elevation of intraocular pressure (IOP) in a rat glaucoma model. methods …

Three experimental glaucoma models in rats: comparison of the effects of intraocular pressure elevation on retinal ganglion cell size and death

JH Urcola, M Hernández, E Vecino - Experimental eye research, 2006 - Elsevier
Glaucoma is a chronic and progressive optic nerve neuropathy involving the death of retinal
ganglion cells (RGCs). Elevated intraocular pressure (IOP) is considered to be the major risk …

Neuroprotection in glaucoma: animal models and clinical trials

M Almasieh, LA Levin - Annual review of vision science, 2017 - annualreviews.org
Glaucoma is a progressive neurodegenerative disease that frequently results in irreversible
blindness. Glaucoma causes death of retinal ganglion cells (RGCs) and their axons in the …

Intraocular pressure in genetically distinct mice: an update and strain survey

OV Savinova, F Sugiyama, JE Martin, SI Tomarev… - BMC genetics, 2001 - Springer
Background Little is known about genetic factors affecting intraocular pressure (IOP) in mice
and other mammals. The purpose of this study was to determine the IOPs of genetically …