Bladder cancer diagnosis and follow-up: the current status and possible role of extracellular vesicles

E Oeyen, L Hoekx, S De Wachter, M Baldewijns… - International journal of …, 2019 - mdpi.com
Diagnostic methods currently used for bladder cancer are cystoscopy and urine cytology.
Cystoscopy is an invasive tool and has low sensitivity for carcinoma in situ. Urine cytology is …

[HTML][HTML] Urine biopsy technologies: Cancer and beyond

CK Chen, J Liao, MS Li, BL Khoo - Theranostics, 2020 - ncbi.nlm.nih.gov
Since the discovery of circulating tumor cells in 1869, technological advances in the study of
biomarkers from liquid biopsy have made it possible to diagnose disease in a less invasive …

Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders

AJ Schaser, VR Osterberg, SE Dent, TL Stackhouse… - Scientific reports, 2019 - nature.com
Alpha-synuclein is a presynaptic protein that forms abnormal cytoplasmic aggregates in
Lewy body disorders. Although nuclear alpha-synuclein localization has been described, its …

Novel urinary biomarkers for the detection of bladder cancer: a systematic review

WS Tan, WP Tan, MY Tan, P Khetrapal, L Dong… - Cancer treatment …, 2018 - Elsevier
Background Urinary biomarkers for the diagnosis of bladder cancer represents an area of
considerable research which has been tested in both patients presenting with haematuria …

The tumorigenic roles of the cellular REDOX regulatory systems

SA Castaldo, JR Freitas, NV Conchinha… - Oxidative medicine …, 2016 - Wiley Online Library
The cellular REDOX regulatory systems play a central role in maintaining REDOX
homeostasis that is crucial for cell integrity, survival, and proliferation. To date, a substantial …

A systematic review of the diagnostic and prognostic value of urinary protein biomarkers in urothelial bladder cancer

JJ D'Costa, JC Goldsmith, JS Wilson… - Bladder …, 2016 - content.iospress.com
For over 80 years, cystoscopy has remained the gold-standard for detecting tumours of the
urinary bladder. Since bladder tumours have a tendency to recur and progress, many …

[HTML][HTML] Urine protein biomarkers for the detection, surveillance, and treatment response prediction of bladder cancer

A Chakraborty, S Dasari, W Long… - American journal of …, 2019 - ncbi.nlm.nih.gov
The “gold standard” diagnostic procedure for bladder cancer is cystoscopy, a technique that
can be invasive, expensive, and a possible cause of urinary tract infection. Unlike …

Comprehensive proteomics and platform validation of urinary biomarkers for bladder cancer diagnosis and staging

K Vanarsa, J Castillo, L Wang, KH Lee, C Pedroza… - BMC medicine, 2023 - Springer
Background Bladder cancer (BC) is among the most common cancers diagnosed in men in
the USA. The current gold standards for the diagnosis of BC are invasive or lack the …

[HTML][HTML] Liquid biopsy in urothelial carcinoma: Detection techniques and clinical applications

S Wu, R Li, Y Jiang, J Yu, J Zheng, Z Li, M Li… - Biomedicine & …, 2023 - Elsevier
The types of urothelial carcinoma (UC) include urothelial bladder cancer and upper tract
urothelial carcinoma. Current diagnostic techniques cannot meet the needs of patients …

Protein biomarker discovery studies on urinary sEV fractions separated with UF-SEC for the first diagnosis and detection of recurrence in bladder cancer patients

S Jordaens, E Oeyen, H Willems, F Ameye… - Biomolecules, 2023 - mdpi.com
Urinary extracellular vesicles (EVs) are an attractive source of bladder cancer biomarkers.
Here, a protein biomarker discovery study was performed on the protein content of small …