Many psychiatric illnesses are associated with early mortality and with an increased risk of
developing physical diseases that are more typically seen in the elderly. Moreover, certain …

Under stressful conditions, cellular heme catabolism to carbon monoxide, iron and biliverdin
is mediated by the 32 kDa enzyme, heme oxygenase-1 (HO-1). A wide range of pro-oxidant …

Objective Disturbances in the kynurenine pathway have been implicated in the
pathophysiology of psychotic and mood disorders, as well as several other psychiatric …

Background: Schizophrenia is associated with increased physical morbidity and early
mortality, suggesting that the aging process may be accelerated in schizophrenia. However …

The process of development depends on a number of signaling systems that regulates the
progressive sequence of developmental events. Infertility and neurodevelopmental …

Schizophrenia patients show signs of accelerated aging in cognitive and physiological
domains. Both schizophrenia and accelerated aging, as measured by MRI brain images and …

Schizophrenia has been suggested as a syndrome of accelerated aging. Telomere length
(TL) decrease is considered one biological marker associated with age and can be …

Schizophrenia, like many other human diseases, particularly neuropsychiatric diseases,
shows evidence of accelerated brain aging. The molecular nature of the process of aging is …

Objective: National Death Index data were examined to describe mortality patterns among
older veterans who are homeless. Methods: Homelessness and health care records from the …

Background Schizophrenia is linked with early medical comorbidity and mortality. These
observations indicate possible “accelerated biological aging” in schizophrenia, although …