[HTML][HTML] Therapeutic targeting of STING-TBK1-IRF3 signalling ameliorates chronic stress induced depression-like behaviours by modulating neuroinflammation and …

N Duan, Y Zhang, S Tan, J Sun, M Ye, H Gao… - Neurobiology of …, 2022 - Elsevier
Stress is well known to contribute to the development of both neurological and psychiatric
diseases. In the central nervous system, a role for STING (stimulator of interferon genes) in …

Therapeutic STING activation boosts microglia phagocytosis and ameliorates depression-like behaviors during chronic restraint stress

Q Zhai, Y Zhang, S Tan, J Sun, M Ye, H Gao, K Pu… - 2021 - researchsquare.com
Background The STING-TBK1-IRF3 signaling pathway involves in modulating host innate
immunity, however, the potential role of STING signaling pathway in chronic restraint stress …