Over the past decade, our understanding of the role of stress in serious mental illness has
become more sophisticated. In this paper, we revisit the neural diathesis-stress model of …

Overexposure of the developing fetus to glucocorticoids is hypothesised to be one of the key
mechanisms linking early life development with later life disease. The maternal …

Background Schizophrenia is associated with impaired antioxidant defense, including
abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters. We …

Oxidative stress has been suggested to contribute to the pathophysiology of schizophrenia.
In particular, oxidative damage to lipids, proteins, and DNA as observed in schizophrenia is …

Diathesis-stress models of schizophrenia and other psychotic disorders have dominated
theorizing about etiology for over three decades. More recently, with advances in our …

Over a billion people worldwide are affected by vitamin D deficiency. Although vitamin D
deficiency is associated with impaired cognition, the mechanisms mediating this link are …

The allostatic load (AL) model represents an interdisciplinary approach to comprehensively
conceptualize and quantify chronic stress in relation to pathologies throughout the life cycle …

Oxidative stress has been implicated in the pathophysiology of many neuropsychiatric
disorders such as schizophrenia, bipolar disorder, major depression etc. Both genetic and …

Increasing evidence indicates that oxidative damage exists in schizophrenia. Available
literature about possible mechanisms of oxidative stress induction was reviewed …

Increased peripheral levels of morning cortisol have been reported in people with
schizophrenia (SZ) and bipolar disorder (BD), but findings are inconsistent and few studies …