Mating type in Saccharomyces cerevisiae is determined by two nonhomologous alleles,
MAT a and MAT α. These sequences encode regulators of the two different haploid mating …

Saccharomyces cerevisiae is one of the best-understood and most powerful genetic model
systems. Several disciplines are now converging to turn Saccharomyces into an exciting …

High-quality, well-annotated genome sequences and standardized laboratory strains fuel
experimental and evolutionary research. We present improved genome sequences of three …

Transcriptional silencing in Saccharomyces cerevisiae occurs at several genomic sites
including the silent mating-type loci, telomeres, and the ribosomal DNA (rDNA) tandem …

Cell differentiation in yeast species is controlled by a reversible, programmed DNA-
rearrangement process called mating-type switching. Switching is achieved by two …

Reproductive isolation is a critical step in the process of speciation. Among the most
important factors driving reproductive isolation are genetic incompatibilities. Whether these …

Resveratrol has also been approved for use in enhancing plant disease resistance and
reducing pesticide use. A number of studies have shown that the disease resistance of crops …

The transcriptional silencing of the cryptic mating-type loci in Saccharomyces cerevisiae is
one of the best-studied models of repressive heterochromatin. However, this type of …

The origin recognition complex (ORC) defines origins of replication and also interacts with
heterochromatin proteins in a variety of species, but how ORC functions in heterochromatin …

Whole-genome sequencing, particularly in fungi, has progressed at a tremendous rate. More
difficult, however, is experimental testing of the inferences about gene function that can be …