Neurons in the mammalian brain are not limited to releasing a single neurotransmitter but
often release multiple neurotransmitters onto postsynaptic cells. Here, we review recent …

Recent data indicate that'classical'neurotransmitters can also act as co-transmitters. This
notion has been strengthened by the demonstration that three vesicular glutamate …

The hypothalamus contains the highest diversity of neurons in the brain. Many of these
neurons can co-release neurotransmitters and neuropeptides in a use-dependent manner …

We define the chemoconnectome (CCT) as the entire set of neurotransmitters,
neuromodulators, neuropeptides, and their receptors underlying chemotransmission in an …

The lateral habenula (LHb) is involved in reward, aversion, addiction and depression
through descending interactions with several brain structures, including the ventral …

Mesoaccumbens fibers are thought to co-release dopamine and glutamate. However, the
mechanism is unclear, and co-release by mesoaccumbens fibers has not been documented …

Basic and clinical observations suggest that the caudal hypothalamus comprises a key node
of the ascending arousal system, but the cell types underlying this are not fully understood …

Solute carriers (SLCs) are the largest family of transmembrane transporters that determine
the exchange of various substances, including nutrients, ions, metabolites, and drugs across …

Electrical stimulation of the dorsal raphe (DR) and ventral tegmental area (VTA) activates the
fibres of the same reward pathway but the phenotype of this pathway and the direction of the …

For decades, it has been thought that glutamate and GABA are released by distinct neurons.
However, some mouse neurons innervating the lateral habenula (LHb) co-release …