Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the
Transforming Growth Factor-Beta (TGF-β) superfamily. These proteins are essential to many …

Articular cartilage shows limited self-healing ability owing to its low cellularity and
avascularity. Untreated cartilage defects display an increased propensity to degenerate …

The fast osteogenesis of the large alveolar fossa and the maintenance of the height of the
alveolar ridge after tooth extraction have always been a clinical challenge. Therefore, this …

Osteoarthritis (OA) is a common degenerative joint disease that often involves progressive
cartilage degeneration and bone destruction of subchondral bone. At present, clinical …

Background Osteoarthritis (OA) is a chronic degenerative disease that is one of the main
causes of disability in middle-aged and elderly people. Adipose stem cell (ASC)-derived …

Angiogenesis is a critical process in the formation of new capillaries and a key participant in
rheumatoid arthritis (RA) pathogenesis. Vascular endothelial growth factor (VEGF) …

The pro‐inflammatory cytokine interleukin 1 beta (IL‐1β) plays a critical role in osteoarthritis
(OA) disease pathogenesis. MicroRNA (miRNA) activity is related to inflammation in OA and …

After cartilage damage, a large number of monocytes/macrophages infiltrate into adjacent
synovium and the resident macrophages in synovial tissue transform to activated …