The concept of a scaffold concerns many aspects at different steps on the drug development
path. In medicinal chemistry, the choice of relevant “drug-likeness” scaffold is a starting point …

Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …

Non-Steroidal biologically active heterocyclic compounds 4-(2-(4-chlorophenyl) benzo [d]
thiazol-3 (2H)-yl)-N-((3-substituted-2-hydrobenzo [d] thiazol-2-yl) methylene) thiazol-2 …

Benzothiazole, a fused heterocyclic moiety, has attracted synthetic and medicinal chemists
for good reasons. It is a valuable scaffold that possesses diverse biological activities, such …

Cancer and oxidative stress are interrelated, with reactive oxygen species (ROS) playing
crucial roles in physiological processes and oncogenesis. Excessive ROS levels can induce …

A library of new phenstatin based indole linked chalcone compounds (9a-z and 9aa-ad)
were designed and synthesized. Of these, compound 9a with 1-methyl, 2-and 3-methoxy …

We present a new efficient green synthetic protocol for introduction of substituents to the C-6
position of 2-arylbenzothiazole nuclei. Newly synthesized compounds were designed to …

On the basis and continuation of our previous studies on anti-tubulin and anti-gastric cancer
agents, novel tertiary amide derivatives incorporating benzothiazole moiety were …

This review presents the detailed account of factors leading to cancer and design strategy
for the synthesis of benzimidazole derivatives as anticancer agents. The recent survey for …

Targeted therapy plays a pivotal role in cancer therapeutics by countering the drawbacks of
conventional treatment like adverse events and drug resistance. Over the last decade …