Antidiabetic phytochemicals from medicinal plants: prospective candidates for new drug discovery and development

S Alam, MMR Sarker, TN Sultana… - Frontiers in …, 2022 - frontiersin.org
Diabetes, a chronic physiological dysfunction affecting people of different age groups and
severely impairs the harmony of peoples' normal life worldwide. Despite the availability of …

Flavonoids and type 2 diabetes: Evidence of efficacy in clinical and animal studies and delivery strategies to enhance their therapeutic efficacy

T Hussain, B Tan, G Murtaza, G Liu, N Rahu… - Pharmacological …, 2020 - Elsevier
Diabetes mellitus type 2 (T2DM) is a metabolic disorder develops due to the overproduction
of free radicals where oxidative stress could contribute it. Possible factors are defective …

Influence of vitamin D on islet autoimmunity and beta-cell function in type 1 diabetes

M Infante, C Ricordi, J Sanchez, MJ Clare-Salzler… - Nutrients, 2019 - mdpi.com
Type 1 diabetes (T1D) is a chronic autoimmune disease leading to immune-mediated
destruction of pancreatic beta cells, resulting in the need for insulin therapy. The incidence …

A bittersweet response to infection in diabetes; targeting neutrophils to modify inflammation and improve host immunity

R Dowey, A Iqbal, SR Heller, I Sabroe… - Frontiers in …, 2021 - frontiersin.org
Chronic and recurrent infections occur commonly in both type 1 and type 2 diabetes (T1D,
T2D) and increase patient morbidity and mortality. Neutrophils are professional phagocytes …

The role of vitamin D and its molecular bases in insulin resistance, diabetes, metabolic syndrome, and cardiovascular disease: state of the art

C Argano, L Mirarchi, S Amodeo, V Orlando… - International Journal of …, 2023 - mdpi.com
In the last decade, an increasing awareness was directed to the role of Vitamin D in non-
skeletal and preventive roles for chronic diseases. Vitamin D is an essential hormone in …

Dietary plant flavonoids in prevention of obesity and diabetes

B Dinda, M Dinda, A Roy, S Dinda - Advances in protein chemistry and …, 2020 - Elsevier
Obesity and diabetes are the most prevailing chronic metabolic diseases worldwide from
mainly lipid and glucose metabolic dysfunctions and their incidence is increasing at an …

Probiotics and prebiotics for the amelioration of type 1 diabetes: present and future perspectives

S Mishra, S Wang, R Nagpal, B Miller, R Singh… - Microorganisms, 2019 - mdpi.com
Type 1-diabetes (T1D) is an autoimmune disease characterized by immune-mediated
destruction of pancreatic beta (β)-cells. Genetic and environmental interactions play an …

The oral microbiome in autoimmune diseases: friend or foe?

X Huang, X Huang, Y Huang, J Zheng, Y Lu… - Journal of Translational …, 2023 - Springer
The human body is colonized by abundant and diverse microorganisms, collectively known
as the microbiome. The oral cavity has more than 700 species of bacteria and consists of …

Modulating the foreign body response of implants for diabetes treatment

BN Kharbikar, GS Chendke, TA Desai - Advanced drug delivery reviews, 2021 - Elsevier
Diabetes Mellitus is a group of diseases characterized by high blood glucose levels due to
patients' inability to produce sufficient insulin. Current interventions often require implants …

Immunomodulatory effect of vitamin D and its potential role in the prevention and treatment of type 1 diabetes mellitus—A narrative review

K Rak, M Bronkowska - Molecules, 2018 - mdpi.com
Type 1 diabetes mellitus is a chronic autoimmune disease associated with degeneration of
pancreatic β-cells that results in an inability to produce insulin and the need for exogenous …