[HTML][HTML] Long noncoding RNAs: recent insights into their role in male infertility and their potential as biomarkers and therapeutic targets

S Zhao, N Heng, B Weldegebriall Sahlu… - International Journal of …, 2021 - mdpi.com
Long noncoding RNAs (lncRNAs) are composed of nucleotides located in the nucleus and
cytoplasm; these are transcribed by RNA polymerase II and are greater than 200 nt in …

[HTML][HTML] The role of long noncoding RNAs on male infertility: A systematic review and in silico analysis

MA Kyrgiafini, T Sarafidou, Z Mamuris - Biology, 2022 - mdpi.com
Simple Summary Male infertility is a health problem affecting a huge number of couples
worldwide. For many years, scientists have focused on protein-coding genes to explore the …

LncRNA MALAT1 signaling pathway and clinical applications in overcome on cancers metastasis

M Mazarei, V Shahabi Rabori, N Ghasemi… - Clinical and …, 2023 - Springer
In spite of its high mortality rate and difficulty in finding a cure, scientific advancements have
contributed to a reduction in cancer-related fatalities. Aberrant gene expression during …

Long noncoding RNAs in human reproductive processes and diseases

L Zhang, H Sun, X Chen - Molecular Reproduction and …, 2024 - Wiley Online Library
Infertility has become a global disease burden. Although assisted reproductive technologies
are widely used, the assisted reproduction birth rate is no more than 30% worldwide …

Circular RNAs: novel biomarkers in spermatogenesis defects and male infertility

M Saberiyan, E Karimi, A Safi, P Movahhed… - Reproductive …, 2023 - Springer
Circular RNAs (circRNAs) are a new class of endogenous non-coding RNAs involved in
several cellular and biological processes, including gene expression regulation, microRNA …

Reduced expression of CFAP44 and CFAP44‐AS1 may affect sperm motility and morphology

A Kamel, M Saberiyan, R Mirfakhraie, H Teimori - Andrologia, 2022 - Wiley Online Library
Motility and morphology are two important characteristics of a fertile spermatozoon. CFAP44
gene encodes flagellar protein 44 involved in the formation and function of the flagella and …

[HTML][HTML] Exploring the regulatory role of Linc00893 in asthenozoospermia: Insights into sperm motility and SSC viability

H Lu, D Xu, L Zhao, H Ruan… - Molecular …, 2024 - build.spandidos-publications.com
The role of long intergenic noncoding RNA 00893 (Linc00893) in asthenozoospermia (AS)
and its impact on sperm motility remains unclear The present study explored the effect of …

[HTML][HTML] Sperm epigenetics and male infertility: unraveling the molecular puzzle

M Hosseini, A Khalafiyan, M Zare, H Karimzadeh… - Human Genomics, 2024 - Springer
Background The prevalence of infertility among couples is estimated to range from 8 to 12%.
A paradigm shift has occurred in understanding of infertility, challenging the notion that it …

[HTML][HTML] Homozygous mutation in SLO3 leads to severe asthenoteratozoospermia due to acrosome hypoplasia and mitochondrial sheath malformations

M Lv, C Liu, C Ma, H Yu, Z Shao, Y Gao, Y Liu… - Reproductive Biology …, 2022 - Springer
Background Potassium channels are important for the structure and function of the
spermatozoa. As a potassium transporter, the mSlo3 is essential for male fertility as Slo3 …

[PDF][PDF] The Role of Long Noncoding RNAs on Male Infertility: A Systematic Review and In Silico Analysis. Biology 2022, 11, 1510

MA Kyrgiafini, T Sarafidou, Z Mamuris - 2022 - researchgate.net
Male infertility is a complex disorder affecting many couples worldwide. Long noncoding
RNAs (lncRNAs) regulate important cellular processes; however, a comprehensive …