[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
[HTML][HTML] Structural and functional aspects of Ebola virus proteins
S Jain, E Martynova, A Rizvanov, S Khaiboullina… - Pathogens, 2021 - mdpi.com
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …
[PDF][PDF] Ebola viral glycoprotein bound to its endosomal receptor Niemann-Pick C1
Summary Filoviruses, including Ebola and Marburg, cause fatal hemorrhagic fever in
humans and primates. Understanding how these viruses enter host cells could help to …
humans and primates. Understanding how these viruses enter host cells could help to …
Structure and assembly of the Ebola virus nucleocapsid
W Wan, L Kolesnikova, M Clarke, A Koehler, T Noda… - Nature, 2017 - nature.com
Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex at 3.6 Å resolution
Ebola virus causes haemorrhagic fever with a high fatality rate in humans and non-human
primates. It belongs to the family Filoviridae in the order Mononegavirales, which are viruses …
primates. It belongs to the family Filoviridae in the order Mononegavirales, which are viruses …
[HTML][HTML] An effective CTL peptide vaccine for Ebola Zaire Based on Survivors' CD8+ targeting of a particular nucleocapsid protein epitope with potential implications …
Abstract The 2013–2016 West Africa EBOV epidemic was the biggest EBOV outbreak to
date. An analysis of virus-specific CD8+ T-cell immunity in 30 survivors showed that 26 of …
date. An analysis of virus-specific CD8+ T-cell immunity in 30 survivors showed that 26 of …
[HTML][HTML] Identification of interferon-stimulated genes that attenuate Ebola virus infection
M Kuroda, PJ Halfmann, L Hill-Batorski… - Nature …, 2020 - nature.com
Abstract The West Africa Ebola outbreak was the largest outbreak ever recorded, with over
28,000 reported infections; this devastating epidemic emphasized the need to understand …
28,000 reported infections; this devastating epidemic emphasized the need to understand …
[HTML][HTML] The role of nucleoprotein in immunity to human negative-stranded RNA viruses—not just another brick in the viral nucleocapsid
M Šantak, Z Matić - Viruses, 2022 - mdpi.com
Negative-stranded RNA viruses (NSVs) are important human pathogens, including
emerging and reemerging viruses that cause respiratory, hemorrhagic and other severe …
emerging and reemerging viruses that cause respiratory, hemorrhagic and other severe …
[HTML][HTML] Zinc and copper ions differentially regulate prion-like phase separation dynamics of pan-virus nucleocapsid biomolecular condensates
A Monette, AJ Mouland - Viruses, 2020 - mdpi.com
Liquid-liquid phase separation (LLPS) is a rapidly growing research focus due to numerous
demonstrations that many cellular proteins phase-separate to form biomolecular …
demonstrations that many cellular proteins phase-separate to form biomolecular …
[HTML][HTML] Assembly and transport of filovirus nucleocapsids
O Dolnik, S Becker - PLoS Pathogens, 2022 - journals.plos.org
Filovirus-infected cells are characterized by typical cytoplasmic inclusion bodies (IBs)
located in the perinuclear region. The formation of these IBs is induced mainly by the …
located in the perinuclear region. The formation of these IBs is induced mainly by the …