A review of magnet systems for targeted drug delivery

YL Liu, D Chen, P Shang, DC Yin - Journal of Controlled Release, 2019 - Elsevier
Magnetic drug targeting is a method by which magnetic drug carriers in the body are
manipulated by external magnetic fields to reach the target area. This method is potentially …

Multifunctional nanoparticles for brain tumor imaging and therapy

Y Cheng, RA Morshed, B Auffinger, AL Tobias… - Advanced drug delivery …, 2014 - Elsevier
Brain tumors are a diverse group of neoplasms that often carry a poor prognosis for patients.
Despite tremendous efforts to develop diagnostic tools and therapeutic avenues, the …

Transferrin-conjugated magnetic silica PLGA nanoparticles loaded with doxorubicin and paclitaxel for brain glioma treatment

Y Cui, Q Xu, PKH Chow, D Wang, CH Wang - Biomaterials, 2013 - Elsevier
The effective treatment of malignant brain glioma is hindered by the poor transport across
the blood–brain barrier (BBB) and the low penetration across the blood-tumor barrier (BTB) …

Getting drugs across biological barriers

R Yang, T Wei, H Goldberg, W Wang… - Advanced …, 2017 - Wiley Online Library
The delivery of drugs to a target site frequently involves crossing biological barriers. The
degree and nature of the impediment to flux, as well as the potential approaches to …

Magnetic nanoparticles: from fabrication to clinical applications

NTK Thanh - 2012 - books.google.com
Offering the latest information in magnetic nanoparticle (MNP) research, Magnetic
Nanoparticles: From Fabrication to Clinical Applications provides a comprehensive review …

Magnetic targeting of nanoparticles across the intact blood–brain barrier

SD Kong, J Lee, S Ramachandran, BP Eliceiri… - Journal of controlled …, 2012 - Elsevier
Delivery of therapeutic or diagnostic agents across an intact blood–brain barrier (BBB)
remains a major challenge. Here we demonstrate in a mouse model that magnetic …

Magnetic Nanoparticle-Based Approaches to Locally Target Therapy and Enhance Tissue Regeneration In Vivo

R Sensenig, Y Sapir, C MacDonald, S Cohen… - …, 2012 - Taylor & Francis
Magnetic-based systems utilizing superparamagnetic nanoparticles and a magnetic field
gradient to exert a force on these particles have been used in a wide range of biomedical …

Open challenges in magnetic drug targeting

B Shapiro, S Kulkarni, A Nacev, S Muro… - Wiley …, 2015 - Wiley Online Library
The principle of magnetic drug targeting, wherein therapy is attached to magnetically
responsive carriers and magnetic fields are used to direct that therapy to disease locations …

T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field

L Sanz-Ortega, JM Rojas, A Marcos, Y Portilla… - Journal of …, 2019 - Springer
Background T lymphocytes are highly dynamic elements of the immune system with a tightly
regulated migration. T cell-based transfer therapies are promising therapeutic approaches …

Emerging translational research on magnetic nanoparticles for regenerative medicine

Y Gao, J Lim, SH Teoh, C Xu - Chemical Society Reviews, 2015 - pubs.rsc.org
Regenerative medicine, which replaces or regenerates human cells, tissues or organs, to
restore or establish normal function, is one of the fastest-evolving interdisciplinary fields in …