In this review, we describe the developments in the field of naphthalene diimides (NDIs)
from 2016 to the presentday. NDIs are shown to be an increasingly interesting class of …

Human civilization has witnessed the use of materials-derived from biomolecules of plants
and animal origin for biomedical applications since ancient era. In recent years, precision …

Nucleic acid sequences able to adopt a G-quadruplex conformation are overrepresented
within the human genome. This evidence strongly suggests that these genomic regions …

KRAS is one of the most highly mutated oncoproteins, which is overexpressed in various
human cancers and implicated in poor survival. The G-quadruplex formed in KRAS …

In the context of developing efficient anticancer therapies aimed at eradicating any sort of
tumors, G-quadruplexes represent excellent targets. Small molecules able to interact with G …

G-quadruplexes are four-stranded nucleic acids structures that can form in guanine-rich
sequences. Following the observation that G-quadruplexes are particularly abundant in …

Guanidine DNA quadruplex (G4-DNA) structures convey a distinctive layer of epigenetic
information that is critical for regulating key biological activities and processes as …

Abstract We present G4-iM Grinder, a system for the localization, characterization and
selection of potential G4s, i-Motifs and higher order structures. A robust and highly …

G‐quadruplexes (G4) are four‐stranded structures formed from guanine‐rich
oligonucleotides. Their defined 3D structures and polymorphic nature set them apart from …

Several G-quadruplex nucleic acid (G4s) ligands have been developed seeking target
selectivity in the past decade. Naphthalene diimide (NDI)-based compounds are particularly …