Insect antimicrobial peptides: potential weapons to counteract the antibiotic resistance

MD Manniello, A Moretta, R Salvia, C Scieuzo… - Cellular and Molecular …, 2021 - Springer
Misuse and overuse of antibiotics have contributed in the last decades to a phenomenon
known as antibiotic resistance which is currently considered one of the principal threats to …

Drosophila Innate Immunity Involves Multiple Signaling Pathways and Coordinated Communication Between Different Tissues

S Yu, F Luo, Y Xu, Y Zhang, LH Jin - Frontiers in Immunology, 2022 - frontiersin.org
The innate immune response provides the first line of defense against invading pathogens,
and immune disorders cause a variety of diseases. The fruit fly Drosophila melanogaster …

Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

The cellular lives of Wolbachia

J Porter, W Sullivan - Nature Reviews Microbiology, 2023 - nature.com
Wolbachia are successful Gram-negative bacterial endosymbionts, globally infecting a large
fraction of arthropod species and filarial nematodes. Efficient vertical transmission, the …

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

M Gulia-Nuss, AB Nuss, JM Meyer… - Nature …, 2016 - nature.com
Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …

Toll-like receptors, associated biological roles, and signaling networks in non-mammals

L Nie, SY Cai, JZ Shao, J Chen - Frontiers in immunology, 2018 - frontiersin.org
The innate immune system is the first line of defense against pathogens, which is initiated by
the recognition of pathogen-associated molecular patterns (PAMPs) and endogenous …

TLR2 and TLR4 mediated host immune responses in major infectious diseases: a review

S Mukherjee, S Karmakar, SPS Babu - Brazilian Journal of Infectious …, 2016 - SciELO Brasil
During the course of evolution, multicellular organisms have been orchestrated with an
efficient and versatile immune system to counteract diverse group of pathogenic organisms …

The Drosophila imd signaling pathway

H Myllymäki, S Valanne, M Rämet - The Journal of Immunology, 2014 - journals.aai.org
The fruit fly, Drosophila melanogaster, has helped us to understand how innate immunity is
activated. In addition to the Toll receptor and the Toll signaling pathway, the Drosophila …

Antimicrobial Peptides from Black Soldier Fly (Hermetia illucens) as Potential Antimicrobial Factors Representing an Alternative to Antibiotics in Livestock Farming

J Xia, C Ge, H Yao - Animals, 2021 - mdpi.com
Simple Summary Microbial resistance to antibiotics is a constant threat to livestock farming,
and unreasonable use of antibiotics has increased the prevalence of infectious diseases in …

Innate humoral immune defences in mammals and insects: The same, with differences?

G Sheehan, A Garvey, M Croke, K Kavanagh - Virulence, 2018 - Taylor & Francis
The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …