The adsorption of biomolecules to the surface of engineered nanomaterials, known as
corona formation, defines their biological identity by altering their surface properties and …

The concept of using mRNA to produce its own medicine in situ in the body makes it an ideal
drug candidate, holding great potential to revolutionize the way we approach medicine. The …

The production and use of plastics has constantly increased over the last 30 years. Over one
third of the plastics is used in disposables, which are discarded within three years of their …

For systemically delivered nanoparticles to reach target tissues, they must first circulate long
enough to reach the target and extravasate there. A challenge is that the particles end up …

In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …

Rapid corona formation is found to affect haemolysis, thrombocyte activation, nanoparticle
uptake and endothelial cell death at an early exposure time. Collectively, depending on the …

Besides the wide use of engineered nanomaterials (NMs) in technical products, their
applications are not only increasing in biotechnology and biomedicine, but also in the …

Vaccines containing novel adjuvant formulations are increasingly reaching advanced
development and licensing stages, providing new tools to fill previously unmet clinical …

Fundamentally, all interactions between the nanoparticle corona complex and the biological
machinery are mediated by physical forces common to all molecular systems. The …

The use of nanoparticles in consumer products, for example, cosmetics, sunscreens, and
electrical devices, has increased tremendously over the past decade despite insufficient …