Recent chemical mixing devices for time-resolved serial femtosecond crystallography

J Park, KH Nam - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Understanding the enzyme reaction mechanism is important for identifying fundamental
biochemical processes and for providing invaluable information for enzyme engineering for …

A snapshot love story: What serial crystallography has done and will do for us

A Henkel, D Oberthür - Biological Crystallography, 2024 - journals.iucr.org
Serial crystallography, born from groundbreaking experiments at the Linac Coherent Light
Source in 2009, has evolved into a pivotal technique in structural biology. Initially pioneered …

Review of serial femtosecond crystallography including the COVID-19 pandemic impact and future outlook

S Botha, P Fromme - Structure, 2023 - cell.com
Serial femtosecond crystallography (SFX) revolutionized macromolecular crystallography
over the past decade by enabling the collection of X-ray diffraction data from nano-or …

Structural Dynamics of Metalloproteins and Redox Enzymology with Mix-and-Inject Time-Resolved Serial Femtosecond Crystallography

FHM Koua, H Han, R Bean - ACS catalysis, 2024 - ACS Publications
Time-resolved serial femtosecond crystallography (tr-SFX) enables the study of
biomolecules in action at room temperature, thus facilitating the construction of in crystallo …

[HTML][HTML] Advanced manufacturing provides tailor-made solutions for crystallography with x-ray free-electron lasers

L Paulson, SR Narayanasamy, ML Shelby… - Structural …, 2024 - pubs.aip.org
Serial crystallography at large facilities, such as x-ray free-electron lasers and synchrotrons,
evolved as a powerful method for the high-resolution structural investigation of proteins that …

[HTML][HTML] Exploring serial crystallography for drug discovery

A Dunge, C Phan, O Uwangue, M Bjelcic… - IUCrJ, 2024 - journals.iucr.org
Structure-based drug design is highly dependent on the availability of structures of the
protein of interest in complex with lead compounds. Ideally, this information can be used to …

[HTML][HTML] Kilohertz droplet-on-demand serial femtosecond crystallography at the European XFEL station FXE

S Perrett, A Fadini, CDM Hutchison… - Structural …, 2024 - pubs.aip.org
X-ray Free Electron Lasers (XFELs) allow the collection of high-quality serial femtosecond
crystallography data. The next generation of megahertz superconducting FELs promises to …

Advanced manufacturing provides tailor-made solutions for crystallography with x-ray free-electron lasers

L Paulson, SR Narayanasamy, ML Shelby, M Frank… - Structural Dynamics, 2024 - osti.gov
Serial crystallography at large facilities, such as x-ray free-electron lasers and synchrotrons,
evolved as a powerful method for the high-resolution structural investigation of proteins that …

Sample delivery for structural biology at the European XFEL

K Dörner, P Smyth, J Schulz - Methods in enzymology, 2024 - pubmed.ncbi.nlm.nih.gov
Serial femtosecond crystallography (SFX) at X-ray free electron lasers (XFELs) is a valuable
technique for time-resolved structural studies on enzymes. This method allows for the …

[图书][B] Breaking the cage–Implementing photocages to address spatiotemporal challenges in chemical biology

E Sandelin - 2024 - gupea.ub.gu.se
Med varje andetag reagerar miljontals av cytokrom c oxidas och konverterar syre till vatten,
samtidigt som den frigjorda energin kan användas för essentiella biokemiska processer …