Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19

X Bi, W Liu, X Ding, S Liang, Y Zheng, X Zhu, S Quan… - Cell reports, 2022 - cell.com
The utility of the urinary proteome in infectious diseases remains unclear. Here, we analyzed
the proteome and metabolome of urine and serum samples from patients with COVID-19 …

Discovery proteomics for COVID-19: where we are now

A McArdle, KE Washington… - Journal of proteome …, 2021 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
coronavirus responsible for the pandemic coronavirus disease 2019 (COVID-19), which has …

The role of kidney injury biomarkers in COVID-19

L Su, J Zhang, Z Peng - Renal Failure, 2022 - Taylor & Francis
Abstract The coronavirus disease-2019 (COVID-19) outbreak has been declared a global
pandemic. COVID-19-associated acute kidney injury (COVID-19 AKI) is related to a high …

Direct hemoperfusion using a polymyxin B‐immobilized polystyrene column for COVID‐19

D Katagiri, M Ishikane, Y Asai, S Izumi… - Journal of Clinical …, 2021 - Wiley Online Library
Objective To evaluate the efficacy and safety of direct hemoperfusion using a polymyxin B‐
immobilized polystyrene column (PMX‐DHP) in severe acute respiratory syndrome …

[HTML][HTML] Evaluation of plasma biomarkers to predict major adverse kidney events in hospitalized patients with COVID-19

S Menez, SG Coca, DG Moledina, Y Wen… - American Journal of …, 2023 - Elsevier
Rationale & Objective Patients hospitalized with COVID-19 are at increased risk for major
adverse kidney events (MAKE). We sought to identify plasma biomarkers predictive of MAKE …

Metformin use in patients hospitalized with COVID-19: Lower inflammation, oxidative stress, and thrombotic risk markers and better clinical outcomes

A Usman, KP Bliden, A Cho, N Walia, C Jerjian… - Journal of Thrombosis …, 2022 - Springer
Diabetes mellitus (DM) is associated with a greater risk of COVID-19 and an increased
mortality when the disease is contracted. Metformin use in patients with DM is associated …

First experience addressing the prognostic utility of novel urinary biomarkers in patients with COVID-19

US Tantry, KP Bliden, A Cho, N Walia… - Open Forum …, 2021 - academic.oup.com
Abstract Urine 11-dehydro-thromboxane B2 (u11-dh-TxB2), 8-hydroxy-2'-deoxyguanosine
(8-OHdG), and liver-type fatty acid binding protein levels (L-FABP) at the time of …

Urinary liver‐type fatty acid binding protein is a biomarker reflecting renal damage and the ameliorative effect of drugs at an early stage of histone‐induced acute …

K Ohata, T Sugaya, HN Nguyen, K Arai… - …, 2024 - Wiley Online Library
Aim Circulated histones play a crucial role in the pathogenesis of infectious diseases and
severe trauma, and it is one of the potential molecular targets for therapeutics. Recently, we …

The impact and treatment of COVID-19 in hemodialysis patients

D Katagiri, K Kikuchi - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Patients with coronavirus disease 2019 (COVID-19) undergoing maintenance
hemodialysis have a poor prognosis and limited treatment options. Methods: This paper …

Blood perfusion with polymyxin B immobilized columns in patients with COVID-19 requiring oxygen therapy

D Katagiri, A Tsukada, S Izumi, Y Shimizu… - Scientific Reports, 2024 - nature.com
Extracorporeal blood purification with polymyxin B immobilized fiber column direct
hemoperfusion (PMX-DHP), is reported to be effective in treating COVID-19 pneumonitis …