Within the limited antifungal armamentarium, the azole antifungals are the most frequent
class used to treat Candida infections. Azole antifungals such as fluconazole are often …

Abstract The European Conference on Infections in Leukaemia (ECIL) updated its
guidelines on antifungal prophylaxis for adults using the grading system of IDSA. The …

Invasive fungal infections (IFI) are an emerging problem worldwide with invasive candidiasis
and candidemia responsible for the majority of cases. This is predominantly driven by the …

Objectives Candidaemia is a serious hazard to hospitalized patients, but European
epidemiological data are restricted to national studies focusing on Northern Europe …

Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in
immunocompromised patients. Patients with hematological malignancies undergoing …

Critically ill patients and patients with haematological cancer are HIV-negative populations
at high risk of invasive fungal infections. In intensive-care units, candidaemia and intra …

The host type I interferon (IFN) pathway is a major signature of inflammation induced by the
human fungal pathogen, Candida albicans. However, the molecular mechanism for …

Background Invasive candidiasis (IC) is a common cause of mortality in solid organ
transplant recipients (OTR s), but knowledge of epidemiology in this population is limited …

The treatment of invasive candidiasis has changed greatly in the past decade and must
continue to evolve if we are to improve outcomes in this serious infection. A review of recent …

Immunocompromised patients account for an increasing proportion of the typical intensive
care unit (ICU) case-mix. Because of the increased availability of new drugs for cancer and …