[HTML][HTML] The importance of vaccination in the context of the COVID-19 pandemic: a brief update regarding the use of vaccines

BAS Machado, KVS Hodel, LMS Fonseca, VC Pires… - Vaccines, 2022 - mdpi.com
The COVID-19 pandemic has led the world to undertake the largest vaccination campaign in
human history. In record time, unprecedented scientific and governmental efforts have …

Lifting non-pharmaceutical interventions following the COVID-19 pandemic–the quiet before the storm?

KB Oh, TM Doherty, V Vetter… - Expert review of vaccines, 2022 - Taylor & Francis
Introduction In the first months of the novel coronavirus (COVID-19) pandemic that begun in
2020, non-pharmaceutical interventions (NPIs) have been adopted worldwide. However, the …

[HTML][HTML] Optimization of storage conditions for lipid nanoparticle-formulated self-replicating RNA vaccines

B Kim, RR Hosn, T Remba, D Yun, N Li… - Journal of Controlled …, 2023 - Elsevier
The recent clinical success of multiple mRNA-based SARS-CoV-2 vaccines has proven the
potential of RNA formulated in lipid nanoparticles (LNPs) in humans, and products based on …

[HTML][HTML] The impact of nucleoside base modification in mRNA vaccine is influenced by the chemistry of its lipid nanoparticle delivery system

MC Bernard, E Bazin, N Petiot, K Lemdani… - … Therapy-Nucleic Acids, 2023 - cell.com
The use of modified nucleosides is an important approach to mitigate the intrinsic
immunostimulatory activity of exogenous mRNA and to increase its translation for mRNA …

[HTML][HTML] A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants …

S McCafferty, AKMA Haque, A Vandierendonck… - Molecular Therapy, 2022 - cell.com
Self-amplifying RNA vaccines may induce equivalent or more potent immune responses at
lower doses compared to non-replicating mRNA vaccines via amplified antigen expression …

[HTML][HTML] An overview of current drugs and prophylactic vaccines for coronavirus disease 2019 (COVID-19)

A Alagheband Bahrami, A Azargoonjahromi… - Cellular & molecular …, 2022 - Springer
Designing and producing an effective vaccine is the best possible way to reduce the burden
and spread of a disease. During the coronavirus disease 2019 (COVID-19) pandemic, many …

[HTML][HTML] COVID-19: why do people refuse vaccination? The role of social identities and conspiracy beliefs: evidence from nationwide samples of Polish adults

M Marchlewska, K Hamer, M Baran, P Górska… - Vaccines, 2022 - mdpi.com
In the present research, we focus on COVID-19 vaccine hesitancy, and empirically examine
how different forms of social identity (defensive vs. secure national identity and identification …

[HTML][HTML] Death after the administration of COVID-19 vaccines approved by EMA: has a causal relationship been demonstrated?

A Maiese, A Baronti, AC Manetti, M Di Paolo… - Vaccines, 2022 - mdpi.com
More than eight billion doses of COVID-19 vaccines have been administered globally so far
and 44.29% of people are fully vaccinated. Pre-authorization clinical trials were carried out …

[HTML][HTML] Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer

N Silva-Pilipich, A Lasarte-Cía, T Lozano… - … Therapy-Nucleic Acids, 2022 - cell.com
Alphavirus vectors based on self-amplifying RNA (saRNA) generate high and transient
levels of transgene expression and induce innate immune responses, making them an …

[HTML][HTML] Influence of nanobubble size distribution on ultrasound-mediated plasmid DNA and messenger RNA gene delivery

H Kida, LB Feril, Y Irie, H Endo, K Itaka… - Frontiers in …, 2022 - frontiersin.org
The use of nanobubbles (NBs) for ultrasound-mediated gene therapy has recently attracted
much attention. However, few studies have evaluated the effect of different NB size …