[HTML][HTML] Consequences of genomic diversity in Mycobacterium tuberculosis

M Coscolla, S Gagneux - Seminars in immunology, 2014 - Elsevier
The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC),
comprises seven phylogenetically distinct lineages associated with different geographical …

Mycobacterium tuberculosis: ecology and evolution of a human bacterium

AL Banuls, A Sanou, NT Van Anh… - Journal of medical …, 2015 - microbiologyresearch.org
Some species of the Mycobacterium tuberculosis complex (MTBC), particularly
Mycobacterium tuberculosis, which causes human tuberculosis (TB), are the first cause of …

Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

CB Ford, RR Shah, MK Maeda, S Gagneux… - Nature …, 2013 - nature.com
A key question in tuberculosis control is why some strains of M. tuberculosis are
preferentially associated with resistance to multiple drugs. We demonstrate that M …

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam

KE Holt, P McAdam, PVK Thai, NTT Thuong, DTM Ha… - Nature …, 2018 - nature.com
To examine the transmission dynamics of Mycobacterium tuberculosis (Mtb) isolated from
tuberculosis patients in Ho Chi Minh City, Vietnam, we sequenced the whole genomes of …

Mechanisms of Drug Resistance in Mycobacterium tuberculosis

Y Zhang, C Vilchèze… - Tuberculosis and the …, 2004 - Wiley Online Library
Drug resistance in tuberculosis (TB) is a particular problem because the lengthy therapy of
at least 6 months makes patient compliance very difficult, which frequently creates drug …

[HTML][HTML] Worldwide occurrence of Beijing/W strains of Mycobacterium tuberculosis: a systematic review

JR Glynn, J Whiteley, PJ Bifani, K Kremer… - Emerging infectious …, 2002 - ncbi.nlm.nih.gov
Strains of the Beijing/W genotype family of Mycobacterium tuberculosis have caused large
outbreaks of tuberculosis, sometimes involving multidrug resistance. This genetically highly …

The Influence of Host and Bacterial Genotype on the Development of Disseminated Disease with Mycobacterium tuberculosis

M Caws, G Thwaites, S Dunstan, TR Hawn… - PLoS …, 2008 - journals.plos.org
The factors that govern the development of tuberculosis disease are incompletely
understood. We hypothesized that some strains of Mycobacterium tuberculosis (M …

A marked difference in pathogenesis and immune response induced by different Mycobacterium tuberculosis genotypes

B Lopez, D Aguilar, H Orozco, M Burger… - Clinical & …, 2003 - academic.oup.com
In the last decade, an unprecedented genetic diversity has been disclosed among
Mycobacterium tuberculosis strains found worldwide. However, well-conserved genotypes …

Global dissemination of the Mycobacterium tuberculosis W-Beijing family strains

PJ Bifani, B Mathema, NE Kurepina, BN Kreiswirth - Trends in microbiology, 2002 - cell.com
A large, genetically related group of Mycobacterium tuberculosis strains, variously called W
or Beijing, is distinguished by specific molecular markers and referred to as the W-Beijing …

Tuberculosis in seals caused by a novel member of the Mycobacterium tuberculosis complex: Mycobacterium pinnipedii sp. nov.

DV Cousins, R Bastida, A Cataldi… - … of systematic and …, 2003 - microbiologyresearch.org
A comparison of Mycobacterium tuberculosis complex isolates from seals (pinnipeds) in
Australia, Argentina, Uruguay, Great Britain and New Zealand was undertaken to determine …