Bright sub-20-nm cathodoluminescent nanoprobes for electron microscopy

MB Prigozhin, PC Maurer, AM Courtis, N Liu… - Nature …, 2019 - nature.com
Electron microscopy has been instrumental in our understanding of complex biological
systems. Although electron microscopy reveals cellular morphology with nanoscale …

The detailed comparison of cell death detected by annexin V-PI counterstain using fluorescence microscope, flow cytometry and automated cell counter in mammalian …

E Koç, S Çelik-Uzuner, U Uzuner, R Çakmak - Journal of Fluorescence, 2018 - Springer
The evaluation of cell wellness is an important task for molecular biology research. This
mainly comprises the assessment for morphology and viability of culturing cells. Annexin V …

Correlative near-infrared light and cathodoluminescence microscopy using Y2O3:Ln, Yb (Ln = Tm, Er) nanophosphors for multiscale, multicolour bioimaging

S Fukushima, T Furukawa, H Niioka, M Ichimiya… - Scientific reports, 2016 - nature.com
This paper presents a new correlative bioimaging technique using Y2O3: Tm, Yb and Y2O3:
Er, Yb nanophosphors (NPs) as imaging probes that emit luminescence excited by both …

High-resolution fast ion microscopy of single whole biological cells

AA Bettiol, Z Mi, F Watt - Applied Physics Reviews, 2016 - pubs.aip.org
High-resolution microscopy techniques have become an essential tool in both biological
and biomedical sciences, enabling the visualization of biological processes at cellular and …

Atmospheric scanning electron microscope system with an open sample chamber: Configuration and applications

H Nishiyama, M Koizumi, K Ogawa, S Kitamura… - Ultramicroscopy, 2014 - Elsevier
An atmospheric scanning electron microscope (ASEM) with an open sample chamber and
optical microscope (OM) is described and recent developments are reported. In this …

Dynamic nano-imaging of label-free living cells using electron beam excitation-assisted optical microscope

M Fukuta, S Kanamori, T Furukawa, Y Nawa, W Inami… - Scientific reports, 2015 - nature.com
Optical microscopes are effective tools for cellular function analysis because biological cells
can be observed non-destructively and non-invasively in the living state in either water or …

Cell structure imaging with bright and homogeneous nanometric light source

M Fukuta, A Ono, Y Nawa, W Inami… - Journal of …, 2017 - Wiley Online Library
Label‐free optical nano‐imaging of dendritic structures and intracellular granules in
biological cells is demonstrated using a bright and homogeneous nanometric light source …

Quantitative intrinsic auto-cathodoluminescence can resolve spectral signatures of tissue-isolated collagen extracellular matrix

MS Zielinski, E Vardar, G Vythilingam… - Communications …, 2019 - nature.com
By analyzing isolated collagen gel samples, we demonstrated in situ detection of spectrally
deconvoluted auto-cathodoluminescence signatures of specific molecular content with …

Development of a direct point electron beam exposure system to investigate the biological functions of subcellular domains in a living biological cell

A Tanaka, W Inami, Y Suzuki, Y Kawata - Micron, 2022 - Elsevier
Electron microscopy studies have demonstrated that the diameter of a focused electron
beam is small enough to probe or manipulate subcellular domains of a single biological cell …

High-resolution, label-free imaging of living cells with direct electron-beam-excitation-assisted optical microscopy

Y Nawa, W Inami, S Lin, Y Kawata, S Terakawa - Optics Express, 2015 - opg.optica.org
High spatial resolution microscope is desired for deep understanding of cellular functions, in
order to develop medical technologies. We demonstrate high-resolution imaging of un …