Genetic polymorphism of glutathione S-transferases: Relevance to neurological disorders

S Dasari, S Gonuguntla, MS Ganjayi, S Bukke… - Pathophysiology, 2018 - Elsevier
Glutathione S-tranferases (GSTs) are phase II drug metabolizing enzymes, they play crucial
role in detoxification of environmental pollutants, carcinogens, drugs, xenobiotics and …

Molecular pharmacology and therapeutic advances of monoterpene perillyl alcohol

L Zhang, G Wang, Z Li, J Yang, H Li, W Wang, Z Li, H Li - Phytomedicine, 2024 - Elsevier
Background Perillyl alcohol (POH) is a aroma monoterpene commonly obtained from
various plants' essential oil. Recently, increasing researches have demonstrated that POH …

Associations between arrhythmia episodes and temporally and spatially resolved black carbon and particulate matter in elderly patients

A Zanobetti, BA Coull, A Gryparis, I Kloog… - Occupational and …, 2014 - oem.bmj.com
Objectives Ambient air pollution has been associated with sudden deaths, some of which
are likely due to ventricular arrhythmias. Defibrillator discharge studies have examined the …

Perillyl alcohol (monoterpene alcohol), limonene

S Shojaei, A Kiumarsi, AR Moghadam, J Alizadeh… - The Enzymes, 2014 - Elsevier
Natural products have a long history of use in traditional medicines and their activities
against different diseases have been the focus of many basic and clinical researches in past …

Orofacial antinociceptive effects of perillyl alcohol associated with codeine and its possible modes of action

RRT Limeira, NV Dantas, JF Tomaz-Morais… - Brazilian Oral …, 2022 - SciELO Brasil
This study evaluated the orofacial antinociceptive effect of (S)-(-)-perillyl alcohol (PA)
associated with codeine (C) and investigated the possible molecular anchorage …

A comprehensive analysis of influence ERCC polymorphisms confer on the development of brain tumors

P Geng, J Ou, J Li, Y Liao, N Wang, G Xie, R Sa… - Molecular …, 2016 - Springer
Within DNA repair genes, there lie a number of single nucleotide polymorphisms that may
impair protein function and attenuate DNA repair capability, resulting in genomic instability …

Genetic contribution of polymorphisms in glutathione S-transferases to brain tumor risk

P Geng, J Li, N Wang, J Ou, G Xie, R Sa, C Liu… - Molecular …, 2016 - Springer
Existing data have shown a major effect of glutathione S-transferase (GST) single-nucleotide
polymorphisms on activities of detoxification-related enzymes, and it is the functional …

[HTML][HTML] Synthesis of the prospective anticancer molecule perillic acid from orange essential oil by the yeast Yarrowia lipolytica

MRR Tappin, FM Knopp, IC Cardoso… - Green and Sustainable …, 2017 - scirp.org
The bioconversion of the hydrophobic and volatile limonene to perillic acid, a potential
anticancer agent, by the yeast Yarrowia lipolytica was studied in two steps. Firstly …

[HTML][HTML] Epstein-Barr virus in gastric cancer and association with 30 bp del-latent membrane protein 1 polymorphism

ERC Santos, MSM Silva, NHS Canedo… - Revista da Associação …, 2023 - SciELO Brasil
SUMMARY OBJECTIVE: This study aimed to determine the frequencies of Epstein-Barr
virus, types 1 and 2 infection, and 30 bp del-latent membrane protein 1 viral polymorphism …

The glioblastoma problem: targeting by combined medicinal chemistry approaches

G Frosina - Current medicinal chemistry, 2015 - ingentaconnect.com
Whilst knowledge of basic biology, diagnosis and prognosis of glioblastoma (GB–WHO
grade IV) are steadily improving, advancements of therapy are discouragingly slow, with the …