Angiogenic growth factors (AGFs) are a class of secreted cytokines related to angiogenesis
that mainly include vascular endothelial growth factors (VEGFs), stromal-derived factor-1 …

Abstract Purpose of Review To summarize the mechanisms of tumor angiogenesis and
resistance to antiangiogenic therapy, and the influence on tumor microenvironment. Recent …

Glioblastomas (GBM) are considered one of the most aggressive tumors of the central
nervous system. The standard treatment for GBM-diagnosed patients implies surgery …

Glioblastoma multiforme (GBM) is a central nervous system disease with poor prognosis.
Curative treatments for GBM involve chemotherapy, radiotherapy, and surgical pathways …

Malignant glioma remains one of the most aggressive intracranial tumors with devastating
clinical outcomes despite the great advances in conventional treatment approaches …

Background HOTAIRM1 is revealed to facilitate the malignant progression of glioma.
Vasculogenic mimicry (VM) is critically involved in glioma progression. Nevertheless, the …

Glioma is the most common malignant tumor in the central nervous system, and its unique
pathogenesis often leads to poor treatment outcomes and prognosis. In 2021, the World …

Glioma is characterized by strong immunosuppression and excessive angiogenesis. Based
on existing reports, it can be speculated that the resistance to anti-angiogenic drug vascular …

Introduction Modeling the blood-brain barrier has long been a challenge for
pharmacological studies. Up to the present, numerous attempts have been devoted to …

The vascular endothelial growth factor (VEGF) family includes key mediators of
vasculogenesis and angiogenesis. VEGFs are secreted by various cells of epithelial and …