The vascular endothelium is a monolayer of cells between the vessel lumen and the
vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized …

Insulin resistance is frequently associated with endothelial dysfunction and has been
proposed to play a major role in cardiovascular diseases. Insulin exerts pro-and anti …

Cardiovascular disease is a major complication of diabetes mellitus, and improved
strategies for prevention and treatment are needed. Endothelial dysfunction contributes to …

Endothelial dysfunction contributes to cardiovascular diseases, including hypertension,
atherosclerosis, and coronary artery disease, which are also characterized by insulin …

insulin because of insulin resistance would thus result in the activation of these
proinflammatory transcription factors and an increase in the expression of the corresponding …

Insulin has important vascular actions to stimulate production of nitric oxide from
endothelium. This leads to capillary recruitment, vasodilation, increased blood flow, and …

Endothelial dysfunction is regarded as an important factor in the pathogenesis of vascular
disease in obesity‐related type 2 diabetes. The imbalance in repair and injury …

Background—Aging is a major risk factor for the development of atherosclerosis and
coronary artery disease. Through a microarray approach, we have identified a microRNA …

Endothelial dysfunction is one manifestation of the many changes induced in the arterial
wall by the metabolic abnormalities accompanying diabetes and insulin resistance. In type 1 …

Epidemiological and clinical studies have indicated that nut consumption could be a healthy
dietary strategy to prevent and treat type 2 diabetes (T2DM) and related cardiovascular …