In recent decades, many sphingolipid enzymes, sphingolipid‐metabolism regulators and
sphingolipid transfer proteins have been isolated and characterized. This review will provide …

In this review focus is given to the metabolic turnover of gangliosides/glycosphingolipids.
The metabolism and accompanying intracellular trafficking of gangliosides …

Glycolipids are a large and heterogeneous family of sphingolipids that form complex
patterns on eukaryotic cell surfaces. This molecular diversity is generated by only a few …

The neuronal Golgi apparatus (GA) localizes to the perinuclear region and dendrites as
tubulo-vesicular structures designated Golgi outposts (GOPs). Current evidence suggests …

Gangliosides—glycosphingolipids that contain sialic acid—are concentrated in plasma
membrane lipid domains that are specialized for cell signaling. Recent evidence indicates …

Glycolipid glycosyltransferases catalyze the stepwise transfer of monosaccharides from
sugar nucleotides to proper glycolipid acceptors. They are Golgi resident proteins that …

Glycosylphosphatidylinositol (GPI)-anchored proteins and glycosphingolipids interact with
each other in the mammalian plasma membranes, forming dynamic microdomains. How …

The synthesis of gangliosides is compartmentalized in the Golgi complex. In most cells,
glycosylation of LacCer, GM3, and GD3 to form higher order species (GA2, GM2, GD2, GM1 …

J. Neurochem.(2011) 117, 589–602. Abstract Brain tissue is characterized by its high
glycosphingolipid content, particularly those containing sialic acid (gangliosides). As a result …

Gangliosides are a family of glycolipids characterized by containing a variable number of
sialic acid residues. Nearly, all animal cells contain at least some class of ganglioside in …