Collective cancer invasion with leader–follower organization is increasingly recognized as a
predominant mechanism in the metastatic cascade. Leader cells support cancer invasion by …

The corneal epithelium is continuously renewed by limbal stem/progenitor cells (LSCs), a
cell population harbored in a highly regulated niche located at the limbus. Dysfunction …

The establishment of an early pro-regenerative niche is crucial for tissue regeneration,.
Gasdermin D (GSDMD)-dependent pyroptosis accounts for the release of inflammatory …

Purpose Inclusion of the preservative benzalkonium chloride (BAC) in ophthalmic solutions
is prevalent, despite the noted potential for exacerbating dry eye disease (DED). Whilst …

In the human cornea, regeneration of the epithelium is regulated by the stem cell reservoir of
the limbus, which is the marginal region of the cornea representing the anatomical and …

Aim: To realize and characterize a new generation of keratin-coated gold nanoparticles (Ker-
AuNPs) as highly efficient photosensitive nanosized therapeutics for plasmonic …

Severe corneal wounds can lead to ulceration and scarring if not promptly and adequately
treated. Hyaluronic acid (HA) has been investigated for the treatment of corneal wounds due …

The functional heterogeneity of resident stem cells that support adult organs is incompletely
understood. Here, we directly visualize the corneal limbus in the eyes of live mice and …

The cornea is the outmost ocular tissue and plays an important role in protecting the eye
from environmental insults. Corneal epithelial wounding provokes pain and fear and …

Migration of epithelial cells is fundamental to multiple developmental processes, epithelial
tissue morphogenesis and maintenance, wound healing and metastasis. While migrating …