Regulation of visceral and epicardial adipose tissue for preventing cardiovascular injuries associated to obesity and diabetes

N González, Z Moreno-Villegas… - Cardiovascular …, 2017 - Springer
Nowadays, obesity is seriously increasing in most of the populations all over the world, and
is associated with the development and progression of high-mortality diseases such as type …

NLRP3 inflammasome: the stormy link between obesity and COVID-19

A Lopez-Reyes, C Martinez-Armenta… - Frontiers in …, 2020 - frontiersin.org
Several countries around the world have faced an important obesity challenge for the past
four decades as the result of an obesogenic environment. This disease has a multifactorial …

High fat/high glucose diet induces metabolic syndrome in an experimental rat model

S Moreno-Fernández, M Garcés-Rimón, G Vera… - Nutrients, 2018 - mdpi.com
Metabolic syndrome (MetS) is defined as a constellation of many metabolic disorders such
as hypertension, impaired glucose tolerance, dyslipidemia and obesity, being this last …

TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue

LA Velazquez-Villegas, A Perino, V Lemos… - Nature …, 2018 - nature.com
Remodelling of energy storing white fat into energy expending beige fat could be a
promising strategy to reduce adiposity. Here, we show that the bile acid-responsive …

[HTML][HTML] Dietary factors promoting brown and beige fat development and thermogenesis

M Okla, J Kim, K Koehler, S Chung - Advances in nutrition, 2017 - Elsevier
Brown adipose tissue (BAT) is a specialized fat tissue that has a high capacity to dissociate
cellular respiration from ATP utilization, resulting in the release of stored energy as heat …

Grape seed proanthocyanidins reduced the overweight of C57BL/6J mice through modulating adipose thermogenesis and gut microbiota

H Du, Q Wang, T Li, D Ren, X Yang - Food & function, 2021 - pubs.rsc.org
Activating the thermogenic function of adipocytes is an attractive therapeutic strategy against
obesity and its associated metabolic complications. Proanthocyanidins are a class of …

Royal jelly ameliorates diet-induced obesity and glucose intolerance by promoting brown adipose tissue thermogenesis in mice

T Yoneshiro, R Kaede, K Nagaya, J Aoyama… - Obesity research & …, 2018 - Elsevier
Introduction Identification of thermogenic food ingredients is potentially a useful strategy for
the prevention of obesity and related metabolic disorders. It has been reported that royal …

AMPK activation protects against diet-induced obesity through Ucp1-independent thermogenesis in subcutaneous white adipose tissue

AE Pollard, L Martins, PJ Muckett, S Khadayate… - Nature …, 2019 - nature.com
Obesity results from a chronic imbalance between energy intake and energy output but
remains difficult to prevent or treat in humans. Adenosine monophosphate (AMP)-activated …

Adaptive facultative diet-induced thermogenesis in wild-type but not in UCP1-ablated mice

G von Essen, E Lindsund, B Cannon… - American Journal of …, 2017 - journals.physiology.org
The significance of diet-induced thermogenesis (DIT) for metabolic control is still debated.
Although obesogenic diets recruit UCP1 and adrenergically inducible thermogenesis, and …

Cinnamaldehyde supplementation prevents fasting‐induced hyperphagia, lipid accumulation, and inflammation in high‐fat diet‐fed mice

P Khare, S Jagtap, Y Jain, RK Baboota, P Mangal… - Biofactors, 2016 - Wiley Online Library
Cinnamaldehyde, a bioactive component of cinnamon, is increasingly gaining interest for its
preventive and therapeutic effects against metabolic complications like type‐2 diabetes. This …