Lipid dosage forms are attractive delivery systems for hydrophobic drug molecules.
Emulsion is one of the popular system since many decades. Pharmaceutical applications of …

Microemulsions are transparent, thermodynamically stable colloidal systems. Over the
recent years, they have been increasingly investigated due to their potential as skin delivery …

Recent advances in nanotechnology have led to the development of nano-scale drugs and
delivery systems to improve drug therapeutic effectiveness. Between the end of′ 50 and the …

Tacrolimus (TAC) suffers from poor cutaneous bioavailability when administered topically
using conventional vehicles with the consequence that although it is indicated for the …

Terbinafine hydrochloride (T-HCl) is recommended for the management of fungal keratitis.
To maintain effective aqueous humor concentrations, frequent instillation of T-HCl drops is …

Pentoxifylline (PTX) is a xanthine derivative indicated in treatment of intermittent claudication
and chronic occlusive arterial diseases. It has low oral bioavailability and short half-life; thus …

Niosomes represent an emerging class of novel vesicular systems. They are composed of
nonionic surfactants which are biodegradable and relatively nontoxic. They were developed …

Superficial fungal infections manifesting the skin have become prevalent today. Even though
there has been a substantial number of antifungal drugs approved for treating topical fungal …

Highlights•Thermodynamic principle provides an insight to understand permeation behavior
and the relation between skin and topical product.•Different determinants such as Log P …

In this study, microemulsion microstructures, key formulation variables, and their relationship
to drug transdermal permeation enhancement were investigated. A microemulsion system …