Dengue virus: epidemiology, biology, and disease aetiology
SK Roy, S Bhattacharjee - Canadian journal of microbiology, 2021 - cdnsciencepub.com
Dengue is a vector-borne viral disease caused by the flavivirus dengue virus (DENV).
Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each …
Approximately 400 million cases and 22 000 deaths occur due to dengue worldwide each …
Biochemistry and molecular biology of flaviviruses
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
Dengue virus
A Murugesan, M Manoharan - Emerging and reemerging viral pathogens, 2020 - Elsevier
Dengue virus (DENV) belongs to the family Flaviviridae, genus Flavivirus. It is a single-
stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus …
stranded positive-sense ribonucleic acid virus with 10,700 bases. The genus Flavivirus …
Seeking heterocyclic scaffolds as antivirals against dengue virus
Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …
Molecular determinants of flavivirus virion assembly
TR Barnard, QH Abram, QF Lin, AB Wang… - Trends in biochemical …, 2021 - cell.com
Virion assembly is an important step in the life cycle of all viruses. For viruses of the
Flavivirus genus, a group of enveloped positive-sense RNA viruses, the assembly step …
Flavivirus genus, a group of enveloped positive-sense RNA viruses, the assembly step …
Dengue virus NS proteins inhibit RIG-I/MAVS signaling by blocking TBK1/IRF3 phosphorylation: dengue virus serotype 1 NS4A is a unique interferon-regulating …
NA Dalrymple, V Cimica, ER Mackow - MBio, 2015 - Am Soc Microbiol
Dengue virus (DENV) replication is inhibited by the prior addition of type I interferon or by
RIG-I agonists that elicit RIG-I/MAVS/TBK1/IRF3-dependent protective responses. DENV …
RIG-I agonists that elicit RIG-I/MAVS/TBK1/IRF3-dependent protective responses. DENV …
Coupling of replication and assembly in flaviviruses
Highlights•Flavivirus replication occurs on modified ER membranes called vesicle packets
(Vp) and membrane vesicles (Ve).•Flavivirus non-structural proteins are implicated in …
(Vp) and membrane vesicles (Ve).•Flavivirus non-structural proteins are implicated in …
ER stress, autophagy, and RNA viruses
Endoplasmic reticulum (ER) stress is a general term for representing the pathway by which
various stimuli affect ER functions. ER stress induces the evolutionarily conserved signaling …
various stimuli affect ER functions. ER stress induces the evolutionarily conserved signaling …
Properties and functions of the dengue virus capsid protein
LA Byk, AV Gamarnik - Annual review of virology, 2016 - annualreviews.org
Dengue virus affects hundreds of millions of people each year around the world, causing a
tremendous social and economic impact on affected countries. The aim of this review is to …
tremendous social and economic impact on affected countries. The aim of this review is to …