Protective efficacy of multiepitope vaccines constructed from common antigens of Eimeria species in chickens

C Chen, J Su, M Lu, L Xu, R Yan, X Li, X Song - Veterinary Research, 2023 - Springer
Clinical avian coccidiosis is typically caused by coinfection with several Eimeria species.
Recombinant protein and DNA vaccines have shown promise in controlling coccidiosis. On …

Structure and evolution of avian immunoglobulins

S Härtle, KE Magor, TW Göbel, F Davison, B Kaspers - Avian immunology, 2022 - Elsevier
Antibodies are essential components of the adaptive immune system and can be found in all
jawed vertebrates. They are produced by B cells, bind to their specific antigen, and protect …

Protective immunity induced by Eimeria common antigen 14–3-3 against Eimeria tenella, Eimeria acervulina and Eimeria maxima

J Liu, L Liu, L Li, D Tian, W Li, L Xu, R Yan, X Li… - BMC Veterinary …, 2018 - Springer
Background Avian coccidiosis is often caused by co-infection with several species of
Eimeria worldwide. Developing a multivalent vaccine with an antigen common to multiple …

[HTML][HTML] Identification of common immunodominant antigens of Eimeria tenella, Eimeria acervulina and Eimeria maxima by immunoproteomic analysis

L Liu, X Huang, J Liu, W Li, Y Ji, D Tian, L Tian… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Clinical chicken coccidiosis is mostly caused by simultaneous infection of several Eimeria
species, and host immunity against Eimeria is species-specific. It is urgent to identify …

Genetic identification of antigens protective against coccidia

DP Blake, MW Shirley, AL Smith - Parasite Immunology, 2006 - Wiley Online Library
The Eimeria species, causative agents of the disease coccidiosis, are genetically complex
protozoan parasites endemic in livestock. Drug resistance remains commonplace among …

Protective Efficacy of Coccidial Common Antigen Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) against Challenge with Three Eimeria Species

L Tian, W Li, X Huang, D Tian, J Liu, X Yang… - Frontiers in …, 2017 - frontiersin.org
Coccidiosis is an intestinal disorder of poultry and often caused by simultaneous infections
of several Eimeria species. GAPDH is one of the immunogenic common antigens among …

Induction of protective immunity against Eimeria tenella, Eimeria necatrix, Eimeria maxima and Eimeria acervulina infections using multivalent epitope DNA vaccines

X Song, Z Ren, R Yan, L Xu, X Li - Vaccine, 2015 - Elsevier
Avian coccidiosis is mostly caused by mixed infection of several Eimeria species under
natural conditions and immunity to avian coccidiosis is largely dependent on T-cell immune …

Development of a new immunodiagnostic tool for poultry coccidiosis using an antigen-capture sandwich assay based on monoclonal antibodies detecting an …

Y Lee, HS Lillehoj - Poultry Science, 2023 - Elsevier
This study was conducted to develop an antigen-capture ELISA that detects an
immunodominant antigen of Eimeria, 3-1E which is present in all Eimeria species, using a …

A review of adaptive immune responses to Eimeria tenella and Eimeria maxima challenge in chickens

SA Mtshali, MA Adeleke - World's Poultry Science Journal, 2020 - Taylor & Francis
Adaptive immune responses in poultry against the invading parasites are complex, involving
both specific and non-specific immunity. Attempts in finding new vaccine candidates for …

Immunoproteomic and mass spectrometric analysis of Eimeria acervulina antigens recognized by antisera from chickens infected with E. acervulina, E. tenella or E …

J Liu, W Tuo, X Wu, J Xiong, E Yu, C Yin, Z Ma, L Liu - Parasites & vectors, 2020 - Springer
Background Coccidiosis is caused by Eimeria spp. and can result in severe economic
losses to the global poultry industry. Due to anticoccidial drug resistance rapidly developing …