Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses

S Guth, S Hüser, A Roth, G Degen, P Diel, K Edlund… - Archives of …, 2020 - Springer
Recently, epidemiological studies have suggested that fluoride is a human developmental
neurotoxicant that reduces measures of intelligence in children, placing it into the same …

Inorganic fluoride and functions of brain

NI Agalakova, OV Nadei - Critical Reviews in Toxicology, 2020 - Taylor & Francis
Although actively disputed and questioned, it has been proposed that chronic exposure to
inorganic fluoride (F−) is toxic for brain. The major question for this review was whether an …

The effects of fluoride in drinking water

L Aggeborn, M Öhman - Journal of Political Economy, 2021 - journals.uchicago.edu
Water fluoridation is a common but debated public policy. In this paper, we use Swedish
registry data to study the causal effects of fluoride in drinking water. We exploit exogenous …

Chlorogenic acid ameliorates memory loss and hippocampal cell death after transient global ischemia

E Hermawati, N Arfian, M Mustofa… - European Journal of …, 2020 - Wiley Online Library
Chlorogenic acid (CGA) is known to have antioxidant potentials, yet the effect of CGA on
brain ischemia has not been sufficiently understood. Brain ischemia such as transient global …

Effects of Quercetin against fluoride-induced neurotoxicity in the medial prefrontal cortex of rats: A stereological, histochemical and behavioral study

P Javanbakht, A Talebinasab, R Asadi-Golshan… - Food and Chemical …, 2025 - Elsevier
Background Exposure to high levels of fluoride leads to brain developmental and functional
damage. Motor performance deficits, learning and memory dysfunctions are related to …

Contribution to the ongoing discussion on fluoride toxicity

S Guth, S Hüser, A Roth, G Degen, P Diel… - Archives of …, 2021 - Springer
Since the addition of fluoride to drinking water in the 1940s, there have been frequent and
sometimes heated discussions regarding its benefits and risks. In a recently published …

Focus on cognitive impairment induced by excessive fluoride: an update review

Y Zhang, Y Gao, X Liu - Neuroscience, 2024 - Elsevier
Fluorosis is a global public health concern. Prolonged exposure to excessive fluoride
causes fluoride accumulation in the hippocampus, resulting in cognitive dysfunction. Cell …

Subchronic administration of high-dose sodium fluoride causes deficits in cerebellar Purkinje cells but not motor coordination of rats

F Agustina, ZM Sofro, G Partadiredja - Biological Trace Element Research, 2019 - Springer
Fluoride is frequently added to drinking water supplies, various food products, toothpaste,
and mouth rinses to prevent tooth damage. However, at high concentrations, fluoride can …

Bone strength in growing rats treated with fluoride: a multi-dose histomorphometric, biomechanical and densitometric study

BL Fina, M Lupo, ER Da Ros, M Lombarte… - Biological trace element …, 2018 - Springer
Bone deformation and fragility are common signs of skeletal fluorosis. Disorganisation of
bone tissue and presence of inflammatory foci were observed after fluoride (F−) …

[PDF][PDF] The Lingzhi Mushroom (Ganoderma lucidum) Extract Reduce the Number of Lymphocyte in Diabetics Rats with Periodontitis: In Vivo Experimental on Sprague …

CC Prihastuti - In Proceedings of the 1st Jenderal Soedirman …, 2021 - scitepress.org
Periodontitis is a chronic inflammation on the periodontal tissue that is characterized by
attachment loss and bone loss. Diabetes mellitus deteriorated the condition of periodontitis …