Idiopathic pulmonary fibrosis is a devastating, age-related lung disease of unknown cause
that has few treatment options. This disease was once thought to be a chronic inflammatory …

This review is an account of how pulmonary damage caused by cigarette smoke and other
environmental toxins can incite inflammatory and immunologic reactions that culminate in …

Extravasation of monocytes into tissue and to the site of injury is a fundamental
immunological process, which requires rapid responses via post translational modifications …

The immunopathology of chronic obstructive pulmonary disease (COPD) is based on the
innate and adaptive inflammatory immune responses to the chronic inhalation of cigarette …

Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation of
the airways and progressive destruction of lung parenchyma, a process that in most cases is …

Rationale and Objectives: The prevalence of chronic obstructive pulmonary disease (COPD)
is age-dependent, suggesting an intimate relationship between the pathogenesis of COPD …

Chronic obstructive pulmonary diseases (COPD), comprised of pulmonary emphysema,
chronic bronchitis, and structural and inflammatory changes of small airways, is a leading …

Several studies have implicated a causative role for specific matrix metalloproteinases
(MMPs) in the development and progression of cigarette smoke-induced chronic obstructive …

Emphysema is one manifestation of a group of chronic, obstructive, and frequently
progressive destructive lung diseases. Cigarette smoking and air pollution are the main …

Rationale: Chronic obstructive pulmonary disease (COPD) is a devastating disease, for
which no causal therapy is available. Objectives: To characterize WNT/β-catenin signaling in …