The ErbB receptor family, also known as the EGF receptor family or type I receptor family,
includes the epidermal growth factor (EGF) receptor (EGFR) or ErbB1/Her1, ErbB2/Her2 …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

Human health is under constant threat of a wide variety of dangers, both self and nonself.
The immune system is occupied with protecting the host against such dangers in order to …

G protein-coupled receptors (GPCRs) constitute the largest and most diverse protein family
in the human genome with over 800 members identified to date. They play critical roles in …

Abstract P2Y receptors are G protein‐coupled receptors (GPCRs) that are activated by
adenine and uridine nucleotides and nucleotide sugars. There are eight subtypes of P2Y …

The role of ATP as an extracellular signalling molecule is now well established and
evidence is accumulating that ATP and other nucleotides (ADP, UTP and UDP) play …

Migraine is the third most common disease worldwide, the most common neurological
disorder, and one of the most common pain conditions. Despite its prevalence, the basic …

Both G protein-coupled receptors (GPCRs) and receptor-tyrosine kinases (RTKs) regulate
large signaling networks, control multiple cell functions and are implicated in many diseases …

P2 receptors for extracellular nucleotides are divided into two categories: the ion channel
receptors (P2X) and the G-protein-coupled receptors (P2Y). For the P2X receptors, signal …

Angiogenesis involves endothelial cell differentiation, proliferation, migration and cord
formation, which lead to tubulogenesis to form vessels. One group of growth factor receptors …