Listeriosis, a model infection to study host-pathogen interactions in vivo

H Kammoun, M Kim, L Hafner, J Gaillard… - Current Opinion in …, 2022 - Elsevier
Highlights•Humanized animal models allow deciphering L. monocytogenes interactions with
host tissues.•L. monocytogenes adapts to challenging environments inside and outside the …

Signals behind Listeria monocytogenes virulence mechanisms

D Meireles, R Pombinho, D Cabanes - Gut Microbes, 2024 - Taylor & Francis
The tight and coordinated regulation of virulence gene expression is crucial to ensure the
survival and persistence of bacterial pathogens in different contexts within their hosts …

The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine

Y Feng, SK Chang, DA Portnoy - Mbio, 2023 - Am Soc Microbiol
Folic acid and its derivatives (folates) play central roles in one-carbon metabolism,
necessary for the synthesis of purines, pyrimidines, and some amino acids. Antifolate drugs …

Listeria monocytogenes utilizes glutathione and limited inorganic sulfur compounds as sources of essential cysteine

JC Berude, P Kennouche, ML Reniere… - Infection and …, 2024 - Am Soc Microbiol
Listeria monocytogenes (Lm) is a Gram-positive facultative intracellular pathogen that leads
a biphasic lifecycle, transitioning its metabolism and selectively inducing virulence genes …

Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment

MR Farman, D Petráčková, D Kumar… - Emerging Microbes & …, 2023 - Taylor & Francis
Bordetella pertussis, the causative agent of whooping cough, is an extracellular, strictly
human pathogen. However, it has been shown that B. pertussis cells can escape phagocytic …

Dual-mode colorimetric/fluorometric sensor for the detection of glutathione based on the peroxidase-like activity of carbon quantum dots

H Guan, D Wang, B Sun - Inorganic Chemistry Communications, 2022 - Elsevier
In the current investigation, fluorescent carbon quantum dot nanoparticles were prepared
using hydrothermal method. In order to achieve green preparation, waste corncob was used …

para-Aminobenzoic Acid Biosynthesis Is Required for Listeria monocytogenes Growth and Pathogenesis

Y Zhang, A Anaya-Sanchez, DA Portnoy - Infection and Immunity, 2022 - Am Soc Microbiol
Biosyntheses of para-aminobenzoic acid (PABA) and its downstream folic acid metabolites
are essential for one-carbon metabolism in all life forms and the targets of sulfonamide and …

Mining the Penicillium expansum Genome for Virulence Genes: A Functional-Based Approach to Discover Novel Loci Mediating Blue Mold Decay of Apple Fruit

D Luciano-Rosario, H Peng, VL Gaskins, JM Fonseca… - Journal of Fungi, 2023 - mdpi.com
Blue mold, a postharvest disease of pome fruits, is caused by the filamentous fungus
Penicillium expansum. In addition to the economic losses caused by P. expansum, food …

Identification of genetic elements required for Listeria monocytogenes growth under limited nutrient conditions and virulence by a screening of transposon insertion …

L Narayanan, O Ozdemir, N Alugubelly… - Frontiers in …, 2022 - frontiersin.org
Listeria monocytogenes, the causative agent of listeriosis, displays a lifestyle ranging from
saprophytes in the soil to pathogenic as a facultative intracellular parasite in host cells. In the …

Inflammatory dietary potential is associated with vitamin depletion and gut microbial dysbiosis in early pregnancy

SA Alvernaz, ES Wenzel, U Nagelli, LB Pezley… - Nutrients, 2024 - mdpi.com
Pregnancy alters many physiological systems, including the maternal gut microbiota. Diet is
a key regulator of this system and can alter the host immune system to promote …