Schizophrenia is a severe psychiatric disorder which is worsened substantially by substance
abuse/addiction. Substance abuse affects nearly 50% of individuals with schizophrenia …

Treatments for the positive and negative symptoms of schizophrenia have been explored for
decades, but no completely successful therapy has been found as yet. Metabotropic …

Animal behavioral tests are essential to understand the bases of neurologic and
psychological disorders, which can be evaluated by different methodological and …

Substance use disorders are more prevalent in schizophrenia, but the causal links between
both conditions remain unclear. Maternal immune activation (MIA) is associated with …

Maternal infection during pregnancy is considered a key risk factor for developing
schizophrenia in offspring. There is evidence that maternal exposure to infectious agents is …

Maternal immune activation (MIA) model has been profoundly described as a suitable
approach to study the pathophysiological mechanisms of neuropsychiatric disorders …

There is evidence for increased rates of drug use among schizophrenic patients. However,
the causality in this relationship remains unclear. In the present work, we use a maternal …

Prenatal infections are environmental risk factors for neurodevelopmental disorders. In
addition, traumatic experiences during adolescence in individuals exposed to infections …

Cognitive flexibility is the ability to adjust thinking and behavior based on changing
conditions. Cognitive rigidity has been described in a variety of psychiatric and …

Schizophrenia is a serious mental disease in which patients are showing a wide array of
symptoms as well as several brain abnormalities. Both genetic and environmental factors …