Hallmarks of sex bias in immuno-oncology: mechanisms and therapeutic implications

T Xiao, J Lee, TD Gauntner, M Velegraki… - Nature Reviews …, 2024 - nature.com
Sex differences are present across multiple non-reproductive organ cancers, with male
individuals generally experiencing higher incidence of cancer with poorer outcomes …

The interplay between autophagy and cGAS-STING signaling and its implications for cancer

M Schmid, P Fischer, M Engl, J Widder… - Frontiers in …, 2024 - frontiersin.org
Autophagy is an intracellular process that targets various cargos for degradation, including
members of the cGAS-STING signaling cascade. cGAS-STING senses cytosolic double …

LILRB2 promotes immune escape in breast cancer cells via enhanced HLA-A degradation

Z Jiang, Q Huang, Y Chang, Y Qiu, H Cheng, M Yang… - Cellular Oncology, 2024 - Springer
Purpose Increased expression of leukocyte immunoglobulin-like receptor subfamily B
member 2 (LILRB2) is associated with immune evasion in breast cancer (BC). The aim of …

[HTML][HTML] A review of Ribosome profiling and tools used in Ribo-seq data analysis

MS Limbu, T Xiong, S Wang - Computational and Structural Biotechnology …, 2024 - Elsevier
Translational regulation plays the most critical role in gene expression. Ribosome profiling
sequencing (Ribo-Seq) is one of the methods to study translation and its regulation. It is a …

Uncovering CARD14 features in cancer

J Manils, D Bespalov, D Pino, S Vidal-Guirao… - 2024 - researchsquare.com
Aberrant caspase recruitment domain family member 14 (CARD14) signaling has been
strongly associated with inflammatory skin conditions. CARD14 acts as a scaffold protein …