MicroRNAs in metastasis and the tumour microenvironment

C Solé, CH Lawrie - International Journal of Molecular Sciences, 2021 - mdpi.com
Metastasis is the process whereby cancer cells migrate from the primary tumour site to
colonise the surrounding or distant tissue or organ. Metastasis is the primary cause of …

The roles of extracellular vesicles in gliomas: Challenge or opportunity?

L Huang, J Zhan, Y Li, K Huang, X Zhu, J Li - Life Sciences, 2024 - Elsevier
Gliomas are increasingly becoming a major disease affecting human health, and current
treatments are not as effective as expected. Deeper insights into glioma heterogeneity and …

[HTML][HTML] V-ATPase in glioma stem cells: a novel metabolic vulnerability

AM Storaci, I Bertolini, C Martelli… - … of Experimental & …, 2025 - jeccr.biomedcentral.com
Glioblastoma (GBM) is a lethal brain tumor characterized by the glioma stem cell (GSC)
niche. The V-ATPase proton pump has been described as a crucial factor in sustaining GSC …

Vacuolar Proton-Translocating ATPase May Take Part in the Drug Resistance Phenotype of Glioma Stem Cells

M Giambra, A Di Cristofori, F Raimondo… - International Journal of …, 2024 - mdpi.com
The vacuolar proton-translocating ATPase (V-ATPase) is a transmembrane multi-protein
complex fundamental in maintaining a normal intracellular pH. In the tumoral contest, its role …

Identification and validation of ATP6V1G1-regulated phosphorylated proteins in hepatocellular carcinoma

Y Zhang, L Lu, M Chen, J Nie, X Qin, H Chen - PloS one, 2024 - journals.plos.org
V-ATPase Subunit G1 (ATP6V1G1) is one of the subunits of Vacuolar ATPases. Previous
studies have indicated that ATP6V1G1 plays important roles in hepatocellular carcinoma …

Insights into the Peritumoural Brain Zone of Glioblastoma: CDK4 and EXT2 May Be Potential Drivers of Malignancy

M Giambra, A Di Cristofori, D Conconi… - International Journal of …, 2023 - mdpi.com
Despite the efforts made in recent decades, glioblastoma is still the deadliest primary brain
cancer without cure. The potential role in tumour maintenance and progression of the …

V-ATPase Proton Pump May Take Part to Drug-Resistance Phenotype of Glioma Stem Cells

M Giambra, A Di Cristofori, F Raimondo, R Rigolio… - 2024 - preprints.org
The vacuolar proton translocating ATPase (V-ATPase) is a transmembrane multi-protein
complex fundamental in maintaining a normal intracellular pH. In the tumoral contest, its role …