Intracellular trafficking of transforming growth factor β receptors

I Yakymovych, M Yakymovych… - Acta biochimica et …, 2018 - academic.oup.com
Transforming growth factor β (TGFβ) family members signal via heterotetrameric complexes
of type I (TβRI) and type II (TβRII) dual specificity kinase receptors. The availability of the …

Canonical TGFβ signaling and its contribution to endometrial cancer development and progression—underestimated target of anticancer strategies

PK Zakrzewski - Journal of clinical medicine, 2021 - mdpi.com
Endometrial cancer is one of the leading gynecological cancers diagnosed among women
in their menopausal and postmenopausal age. Despite the progress in molecular biology …

Deep learning in single-molecule imaging and analysis: recent advances and prospects

X Liu, Y Jiang, Y Cui, J Yuan, X Fang - Chemical Science, 2022 - pubs.rsc.org
Single-molecule microscopy is advantageous in characterizing heterogeneous dynamics at
the molecular level. However, there are several challenges that currently hinder the wide …

Single-molecule imaging and tracking of molecular dynamics in living cells

N Li, R Zhao, Y Sun, Z Ye, K He… - National Science …, 2017 - academic.oup.com
Unlike the ensemble-averaging measurements, the single-molecule imaging and tracking
(SMIT) in living cells provides the real-time quantitative information about the locations …

Single-molecule imaging of protein interactions and dynamics

F Luo, G Qin, T Xia, X Fang - Annual Review of Analytical …, 2020 - annualreviews.org
Live-cell single-molecule fluorescence imaging has become a powerful analytical tool to
investigate cellular processes that are not accessible to conventional biochemical …

Surface plasmon–coupled emission imaging for biological applications

M Chen, SH Cao, YQ Li - Analytical and Bioanalytical Chemistry, 2020 - Springer
Fluorescence imaging technology has been extensively applied in chemical and biological
research profiting from its high sensitivity and specificity. Much attention has been devoted to …

Modern trends in biophotonics for clinical diagnosis and therapy to solve unmet clinical needs

C Krafft - Journal of biophotonics, 2016 - Wiley Online Library
This contribution covers recent original research papers in the biophotonics field. The
content is organized into main techniques such as multiphoton microscopy, Raman …

Variable-angle nanoplasmonic fluorescence microscopy: An axially resolved method for tracking the endocytic pathway

M Chen, XH Pan, Q Liu, SX Huo, SH Cao… - Analytical …, 2019 - ACS Publications
The study of endocytosis, which encompasses diverse mechanisms in biology, requires the
utilization of high axial resolution to monitor molecular behavior on both the cell surface and …

Quantitative single-molecule study of TGF-β/Smad signaling

R Zhao, N Li, J Xu, W Li, X Fang - Acta Biochimica et Biophysica …, 2018 - academic.oup.com
TGF-β/Smad signaling pathway triggers diverse cellular responses among different cell
types and environmental conditions. Quantitative analysis of protein-protein interactions …

Nanoscale Distribution of Transforming Growth Factor Receptor on Post‐Golgi Vesicle Revealed by Super‐resolution Microscopy

H Ruan, J Yu, J Yuan, N Li… - Chemistry–An Asian …, 2016 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) type II receptor (TβRII) plays a critical role in the
initiation of TGF‐β signaling pathway; therefore, the study of its synthesis and transport …