Late-stage functionalization (LSF) constitutes a powerful strategy for the assembly or
diversification of novel molecular entities with improved physicochemical or biological …

Redox processes are at the heart of synthetic methods that rely on either electrochemistry or
photoredox catalysis, but how do electrochemistry and photoredox catalysis compare? Both …

The development of synthetic methods for the introduction of the fluorine atom and
fluoroalklyl groups into organic molecules has gained increased attention. Synthetic organic …

Conspectus Transition-metal catalyzed cross-coupling reactions are fundamental reactions
in organic chemistry, facilitating strategic bond formations for accessing natural products …

Selective C–C bond cleavage under mild conditions can serve as a valuable tool for organic
syntheses and macromolecular degradation. However, the conventional chemical methods …

Reactions that enable carbon–nitrogen, carbon–oxygen and carbon–carbon bond formation
lie at the heart of synthetic chemistry. However, substrate prefunctionalization is often …

As the breadth of radical chemistry grows, new means to promote and regulate single-
electron redox activities play increasingly important roles in driving modern synthetic …

Conspectus The appeal and promise of synthetic organic electrochemistry have been
appreciated over the past century. In terms of redox chemistry, which is frequently …

The Kolbe reaction forms carbon-carbon bonds through electrochemical decarboxylative
coupling. Despite more than a century of study, the reaction has seen limited applications …

Herein, a facile and general electroreductive deuteration of unactivated alkyl halides (X= Cl,
Br, I) or pseudo-halides (X= OMs) using D2O as the economical deuterium source was …