The possibility that proteinuria may accelerate kidney disease progression to end-stage
renal failure has received support from the results of increasing numbers of experimental …

The mTOR pathway has a central role in the regulation of cell metabolism, growth and
proliferation. Studies involving selective gene targeting of mTOR complexes (mTORC1 and …

Podocytes are known to play a determining role in the progression of proteinuric kidney
disease. N6-methyladenosine (m6A), as the most abundant chemical modification in …

Abstract The Kasabach-Merritt phenomenon (KMP) in kaposiform hemangioendothelioma
(KHE) is characterized by life-threatening thrombocytopenia and consumptive coagulopathy …

Renal fibrosis is the usual outcome of an excessive accumulation of extracellular matrix
(ECM) that frequently occurs in membranous and diabetic nephropathy. The result of renal …

Inflammation is one of main mechanisms of autoimmune disorders and a common feature of
most diseases. Appropriate suppression of inflammation is a key resolution to treat the …

The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a pivotal
role in mediating cell size and mass, proliferation, and survival. mTOR has also emerged as …

Overcome the toughest clinical challenges in nephrology with the new 9th edition of
Brenner/Rector's The Kidney! A brand-new editorial team of Drs. Maarten W. Taal, Glenn M …

Objectives Temporomandibular joint osteoarthritis (TMJOA) is an inflammatory joint disease.
This study investigated whether exosomes (Exos) of stem cells from human exfoliated …

Age-related disorders such as chronic kidney disease (CKD) are increasingly prevalent
globally and pose unprecedented challenges. In many aspects, CKD can be viewed as a …