Simple Summary Carcinomas and precursor lesions of the biliary tract belong to a spectrum
of pancreatobiliary neoplasms that share common histology and cell lineages. High-grade …

An increasing number of studies investigate the use of neoadjuvant treatment for ductal
adenocarcinoma of the pancreas. While a strong rationale supports this approach, study …

Abstract Background Biliary tract cancers (BTCs) include intrahepatic (IHC), hilar, distal bile
duct (DBD) and gallbladder carcinoma (GBC). Neutrophil/lymphocyte ratio (NLR), a marker …

The role of liver biopsy in the diagnosis of hepatocellular carcinoma (HCC) has been
challenged over time by the ability of imaging techniques to characterize liver lesions in …

Importance Patients with periampullary adenocarcinomas have widely variable survival.
These cancers are traditionally categorized by their anatomic location of origin, namely, the …

Ampullary cancer represents approximately 6% of the malignant periampullary tumors. An
early occurrence of symptoms leads to a 5-year survival rate after curative surgery of 30 to …

Histologic classification of ampullary carcinomas as intestinal versus pancreatobiliary is
rapidly becoming a part of management algorithms, with immunohistochemical classification …

Abstract Background/Objective The benefit of adjuvant therapy in ampullary cancer
(AMPAC) patients following pancreatoduodenectomy (PD) is debated. The aim of this study …

Immunotherapeutic modalities are currently revolutionizing cancer treatment. In pancreatic
cancer, however, early clinical trials have been disappointing. The optimization of …

Background Distal cholangiocarcinoma (DCC) is a rare malignancy and validated
prognostic markers remain scarce. We aimed to evaluate the role of serum CA19-9 as a …