MiR-326: promising biomarker for cancer
YJ Pan, J Wan, CB Wang - Cancer Management and Research, 2019 - Taylor & Francis
MicroRNAs (miRNAs) are small non-coding and highly conserved RNAs that act in
biological processes including cell proliferation, invasion, apoptosis, metabolism, signal …
biological processes including cell proliferation, invasion, apoptosis, metabolism, signal …
Ovarian Cancer and Cancer Stem Cells—Cellular and Molecular Characteristics, Signaling Pathways, and Usefulness as a Diagnostic Tool in Medicine and Oncology
Simple Summary Ovarian cancer is still a high-risk, metastatic disease, often diagnosed at a
late stage. Difficulties in its treatment are associated with high resistance to chemotherapy …
late stage. Difficulties in its treatment are associated with high resistance to chemotherapy …
[HTML][HTML] GSK3β and Gli3 play a role in activation of Hedgehog-Gli pathway in human colon cancer—Targeting GSK3β downregulates the signaling pathway and …
Abstract The role of Hedgehog-Gli (Hh-Gli) signaling in colon cancer tumorigenesis has not
yet been completely elucidated. Here we provide strong evidence of Hh-Gli signaling …
yet been completely elucidated. Here we provide strong evidence of Hh-Gli signaling …
Mechanisms and therapeutic potential of the hedgehog signaling pathway in cancer
G Cong, X Zhu, XR Chen, H Chen, W Chong - Cell Death Discovery, 2025 - nature.com
A sort of major malignant disease, cancer can compromise human health wherever. Some
mechanisms of the occurrence and evolution of cancer still seem elusive even now …
mechanisms of the occurrence and evolution of cancer still seem elusive even now …
[HTML][HTML] Tripartite motif 16 inhibits the migration and invasion in ovarian cancer cells
H Tan, J Qi, G Chu, Z Liu - Oncology research, 2017 - ncbi.nlm.nih.gov
Abstract Tripartite motif 16 (TRIM16), a member of the RING B-box coiled-coil
(RBCC)/tripartite motif (TRIM) protein family, has been shown to play a role in tumor …
(RBCC)/tripartite motif (TRIM) protein family, has been shown to play a role in tumor …
Cyclopamine sensitizes glioblastoma cells to temozolomide treatment through Sonic hedgehog pathway
GB Carballo, D Matias, JH Ribeiro, LS Pessoa… - Life Sciences, 2020 - Elsevier
Aim Glioblastoma is an extremely aggressive glioma, resistant to radio and chemotherapy
usually performed with temozolomide. One of the main reasons for glioblastoma resistance …
usually performed with temozolomide. One of the main reasons for glioblastoma resistance …
Combination of cyclopamine and tamoxifen promotes survival and migration of mcf-7 breast cancer cells–interaction of Hedgehog-Gli and estrogen receptor signaling …
Hedgehog-Gli (Hh-Gli) signaling pathway is one of the new molecular targets found
upregulated in breast tumors. Estrogen receptor alpha (ERα) signaling has a key role in the …
upregulated in breast tumors. Estrogen receptor alpha (ERα) signaling has a key role in the …
Regulation of survivin isoform expression by GLI proteins in ovarian cancer
Ovarian cancer (OC) is the most lethal female gynecological malignancy, mostly due to
diagnosis in late stages when treatment options are limited. Hedgehog-GLI (HH-GLI) …
diagnosis in late stages when treatment options are limited. Hedgehog-GLI (HH-GLI) …
Conditional Inactivation of p53 in Mouse Ovarian Surface Epithelium Does Not Alter MIS Driven Smad2-Dominant Negative Epithelium-Lined Inclusion Cysts or …
Epithelial ovarian cancer is the most lethal gynecological malignancy among US women.
The etiology of this disease, although poorly understood, may involve the ovarian surface …
The etiology of this disease, although poorly understood, may involve the ovarian surface …
Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis
SN Saldanha, TO Tollefsbol - Journal of cellular physiology, 2014 - Wiley Online Library
Cellular pathways are numerous and are highly integrated in function in the control of
cellular systems. They collectively regulate cell division, proliferation, survival and apoptosis …
cellular systems. They collectively regulate cell division, proliferation, survival and apoptosis …