Advances in ligase chain reaction and ligation-based amplifications for genotyping assays: Detection and applications

AA Gibriel, O Adel - Mutation Research/Reviews in Mutation Research, 2017 - Elsevier
Genetic variants have been reported to cause several genetic diseases. Various genotyping
assays have been developed for diagnostic and screening purposes but with certain …

[HTML][HTML] Future microfluidic and nanofluidic modular platforms for nucleic acid liquid biopsy in precision medicine

A Egatz-Gomez, C Wang, F Klacsmann, Z Pan… - …, 2016 - pubs.aip.org
Nucleic acid biomarkers have enormous potential in non-invasive diagnostics and disease
management. In medical research and in the near future in the clinics, there is a great …

Single-reaction, multiplex, real-time rt-PCR for the detection, quantitation, and serotyping of dengue viruses

JJ Waggoner, J Abeynayake, MK Sahoo… - PLoS neglected …, 2013 - journals.plos.org
Background Dengue fever results from infection with one or more of four different serotypes
of dengue virus (DENV). Despite the widespread nature of this infection, available molecular …

Serotype and genotype analysis of dengue virus by sequencing followed by phylogenetic analysis using samples from three mini outbreaks-2007-2009 in Pakistan

Z Fatima, M Idrees, MA Bajwa, Z Tahir, O Ullah… - BMC microbiology, 2011 - Springer
Background Since the first reported outbreak of dengue hemorrhagic fever in Pakistan,
several mini outbreaks have erupted in the region. Dengue virus serotype 3 (DEN-3) was …

In-silico identification and evaluation of plant flavonoids as dengue NS2B/NS3 protease inhibitors using molecular docking and simulation approach

MT ul Qamar, UA Ashfaq, K Tusleem… - Pakistan journal of …, 2017 - go.gale.com
Dengue infection is prevailing among the people not only from the developing countries but
also from the developed countries due to its high morbidity rate around the globe. Hence …

Universal single-probe RT-PCR assay for diagnosis of dengue virus infections

E Alm, B Lesko, G Lindegren, C Ahlm… - PLoS neglected …, 2014 - journals.plos.org
Background Dengue is a mosquito-borne viral disease that has become more prevalent in
the last few decades. Most patients are viremic when they present with symptoms, and early …

Isolation of serotype-specific antibodies against dengue virus non-structural protein 1 using phage display and application in a multiplexed serotyping assay

K Lebani, ML Jones, D Watterson, A Ranzoni… - PloS one, 2017 - journals.plos.org
The multidimensional nature of dengue virus (DENV) infections, which can be caused by
four distinct serotypes of the virus, complicates the sensitivity of assays designed for the …

[HTML][HTML] Molecular docking based screening of plant flavonoids as dengue NS1 inhibitors

MT Ul Qamar, A Mumtaz, R Naseem, A Ali… - …, 2014 - ncbi.nlm.nih.gov
Dengue infection has turned into a serious health concern globally due to its high morbidity
rate and a high possibility of increase in its mortality rate on the account of unavailability of …

[HTML][HTML] Spatial–temporal Co-circulation of dengue virus 1, 2, 3, and 4 associated with coinfection cases in a hyperendemic area of Brazil: a 4-week survey

EHP Andrade, LB Figueiredo, APP Vilela… - The American journal …, 2016 - ncbi.nlm.nih.gov
Dengue is currently regarded as a major public health problem worldwide. In a
hyperendemic region during an outbreak, we detected the co-circulation of all Dengue virus …

[HTML][HTML] Fully integrated thermoplastic genosensor for the highly sensitive detection and identification of multi-drug resistant tuberculosis (MDR-TB)

H Wang, HW Chen, ML Hupert, PC Chen… - … (International ed. in …, 2012 - ncbi.nlm.nih.gov
Published in final edited form as: Angew Chem Int Ed Engl. 2012 April 27; 51 (18): 4349–
4353. doi: 10.1002/anie. 201200732. $ watermark-text $ watermark-text $ watermark-text …