Introduction Intraoperative hypotension is associated with adverse postoperative outcomes;
however these findings are supported only by observational studies. The aim of this meta …

We report a systematic review and meta-analysis of published randomised controlled trials
evaluating the efficacy of tranexamic acid (TXA) in reducing blood loss and transfusion in …

Background context Spine surgery is usually associated with large amount of blood loss,
necessitating blood transfusions. Blood loss-associated morbidity can be because of direct …

Purpose Studies have shown that tranexamic acid (TXA) reduces blood loss and transfusion
need in patients undergoing total knee arthroplasty (TKA). However, no single study has …

Antifibrinolytic drugs have become almost ubiquitous in their use during major surgery when
bleeding is expected or commonplace. Inhibition of the fibrinolytic pathway after tissue injury …

Background Studies have shown that tranexamic acid reduces blood loss and transfusion
need in patients undergoing total hip arthroplasty. However, no to date, no study has been …

So far, studies of topical tranexamic acid (TXA) in total hip arthroplasty (THA) were still
lacking and controversial. We conducted this randomized double-blind controlled trial which …

Background Conflicting reports have been published regarding the effect of tranexamic acid
(TXA) on reducing blood loss and transfusion in patients undergoing orthopedic surgery. We …

In this study, we evaluated the hemostatic effects of tranexamic acid (TNA), an antifibrinolytic
drug, by examining the timing of its administration during total hip arthroplasty. One hundred …

Background Tranexamic acid (TXA) is well-established as a versatile oral, intramuscular,
and intravenous (IV) antifibrinolytic agent. However, the efficacy of IV TXA in reducing …