Fenton chemistry: an introduction

P Wardman, LP Candeias - Radiation research, 1996 - meridian.allenpress.com
In 1876, Fenton described a colored product obtained on mixing tartaric acid with hydrogen
peroxide and a low concentration of a ferrous salt. Full papers in 1894 and 1896 showed the …

CC‐1065 and the duocarmycins: understanding their biological function through mechanistic studies

DL Boger, DS Johnson - Angewandte Chemie International …, 1996 - Wiley Online Library
We review here studies defining the DNA alkylation properties of a class of potent antitumor
antibiotics that includes CC‐1065 and the duocarmycins, as well as investigations that …

Ru(II)-p-Cymene Complexes of Furoylthiourea Ligands for Anticancer Applications against Breast Cancer Cells

DP Dorairaj, J Haribabu, M Dharmasivam… - Inorganic …, 2023 - ACS Publications
Half-sandwich Ru (II) complexes containing nitro-substituted furoylthiourea ligands, bearing
the general formula [(η 6-p-cymene) RuCl2 (L)](1–6) and [(η 6-p-cymene) RuCl …

Mixed-ligand copper (II)-phenolate complexes: effect of coligand on enhanced DNA and protein binding, DNA cleavage, and anticancer activity

V Rajendiran, R Karthik, M Palaniandavar… - Inorganic …, 2007 - ACS Publications
The copper (II) complex [Cu (tdp)(ClO4)]· 0.5 H2O (1), where H (tdp) is the tetradentate
ligand 2-[(2-(2-hydroxyethylamino) ethylimino) methyl] phenol, and the mixed ligand …

Evaluation of DNA binding, DNA cleavage, protein binding and in vitro cytotoxic activities of bivalent transition metal hydrazone complexes

P Krishnamoorthy, P Sathyadevi, AH Cowley… - European journal of …, 2011 - Elsevier
Abstract Divalent Co, Ni and Cu hydrazone complexes containing [N′-(phenyl (pyridine-2-
yl) methylidene) benzohydrazide] ligand were synthesised and characterised. Interactions of …

Visible‐light‐induced annihilation of tumor cells with platinum–porphyrin conjugates

A Naik, R Rubbiani, G Gasser… - Angewandte Chemie, 2014 - Wiley Online Library
Despite the extensive use of porphyrins in photodynamic therapy (PDT), tetraplatinated
porphyrins have so far not been studied for their anticancer properties. Herein, we report the …

Synthesis, electronic structure, DNA and protein binding, DNA cleavage, and anticancer activity of fluorophore-labeled copper (II) complexes

SS Bhat, AA Kumbhar, H Heptullah, AA Khan… - Inorganic …, 2011 - ACS Publications
Two mononuclear fluorophore-labeled copper (II) complexes [Cu (nip)(acac)]+(2) and [Cu
(nip) 2] 2+(3), where fluorophore is 2-(naphthalen-1-yl)-1 H-imidazo [4, 5-f][1, 10] …

New ruthenium (II) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and …

M Ganeshpandian, R Loganathan, E Suresh… - Dalton …, 2014 - pubs.rsc.org
A series of half-sandwich Ru (II) arene complexes of the type [Ru (η6-arene)(L) Cl](PF6) 1–
4, where arene is benzene (1, 2) or p-cymene (3, 4) and L is N-methylhomopiperazine (L1) …

Induction of Cell Death by Ternary Copper(II) Complexes of l-Tyrosine and Diimines: Role of Coligands on DNA Binding and Cleavage and Anticancer Activity

S Ramakrishnan, V Rajendiran… - Inorganic …, 2009 - ACS Publications
The mononuclear mixed ligand copper (II) complexes of the type [Cu (l-tyr)(diimine)](ClO4),
where tyr is l-tyrosine and diimine is 2, 2′-bipyridine (bpy)(1), 1, 10-phenanthroline …

Ternary dinuclear copper (II) complexes of a hydroxybenzamide ligand with diimine coligands: the 5, 6-dmp ligand enhances DNA binding and cleavage and induces …

S Ramakrishnan, D Shakthipriya, E Suresh… - Inorganic …, 2011 - ACS Publications
The dinuclear copper (II) complexes [Cu2 (LH) 2 (diimine) 2 (ClO4) 2](ClO4) 2 (1–4), where
LH= 2-hydroxy-N-[2-(methylamino) ethyl] benzamide and diimine= 2, 2′-bipyridine (bpy; 1) …