A comprehensive review on collagen type I development of biomaterials for tissue engineering: From biosynthesis to bioscaffold

IN Amirrah, Y Lokanathan, I Zulkiflee, MFMR Wee… - Biomedicines, 2022 - mdpi.com
Collagen is the most abundant structural protein found in humans and mammals, particularly
in the extracellular matrix (ECM). Its primary function is to hold the body together. The …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts

M Rafat, M Jabbarvand, N Sharma, M Xeroudaki… - Nature …, 2023 - nature.com
Visual impairment from corneal stromal disease affects millions worldwide. We describe a
cell-free engineered corneal tissue, bioengineered porcine construct, double crosslinked …

[HTML][HTML] Corneal structure and transparency

KM Meek, C Knupp - Progress in retinal and eye research, 2015 - Elsevier
The corneal stroma plays several pivotal roles within the eye. Optically, it is the main
refracting lens and thus has to combine almost perfect transmission of visible light with …

Bioinspired fabrication of high strength hydrogels from non-covalent interactions

W Wang, Y Zhang, W Liu - Progress in Polymer Science, 2017 - Elsevier
In nature, many soft supporting tissues capable of withstanding multiform external forces
during various activities consist of high strength hydrogels (HSHGs) in their delicately …

Recent advances on silver nanoparticle and biopolymer-based biomaterials for wound healing applications

SSD Kumar, NK Rajendran, NN Houreld… - International journal of …, 2018 - Elsevier
Silver nanoparticles (AgNPs) are classified as metal-based nanoparticles and have gained
considerable attention amongst researchers in wound healing applications, owing to their …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

In vivo confocal microscopy of corneal nerves in health and disease

A Cruzat, Y Qazi, P Hamrah - The ocular surface, 2017 - Elsevier
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

Corneal transplantation

DTH Tan, JKG Dart, EJ Holland, S Kinoshita - The Lancet, 2012 - thelancet.com
Corneal transplantation or keratoplasty has developed rapidly in the past 10 years.
Penetrating keratoplasty, a procedure consisting of full-thickness replacement of the cornea …

Engineering complex tissues

A Atala, FK Kasper, AG Mikos - Science translational medicine, 2012 - science.org
Tissue engineering has emerged at the intersection of numerous disciplines to meet a
global clinical need for technologies to promote the regeneration of functional living tissues …