Macrocyclic structures are common synthetic targets in drug discovery,(1, 2) and therefore,
interest in their study is continuously increasing in this field.(3, 4) A classic example is …

The rapid emergence of multidrug-resistant pathogens has evolved into a global health
problem as current treatment options are failing for infections caused by pan-resistant …

Abstract Methicillin-Resistant Staphylococcus aureus (MRSA) induced infection calls for
antibacterial agents that are not prone to antimicrobial resistance. We prepare protease …

Bioinspired polymeric materials are attracting increasing attention due to significant
advantages over their natural counterparts: the ability to precisely tune their structures over a …

In the last decade, the field of sequence‐defined polymers and related ultraprecise,
monodisperse synthetic macromolecules has grown exponentially. In the early stage, mainly …

The purpose of this paper is to introduce and highlight a few classes of traditional
antimicrobial peptides with a focus on structure-activity relationship studies. After first …

The development of durable new antiviral therapies is challenging, as viruses can evolve
rapidly to establish resistance and attenuate therapeutic efficacy. New compounds that …

Synthetic macrocycles derived from sequence-defined oligomers are a unique structural
class whose ring size, sequence and structure can be tuned via precise organization of the …

New chemical inhibitors of protein–protein interactions are needed to propel advances in
molecular pharmacology. Peptoids are peptidomimetic oligomers with the capability to …

Synthetic polymers have been extensively exploited for biomedical and pharmacological
applications, spanning from surgical devices, diagnostics, tissue engineering, regenerative …